forgotpwagain

9 ms·

61.
by forgotpwagain 11y ago
Microfluidics is a sexy field. About ten years ago, it was nearing the peak of its first hype peak. This brought a lot of attention to the field and corresponded to the first time people started talking about precision medicine and "li
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by forgotpwagain 11y ago
Computing will help. But we also need new fundamental technologies that get us information that old methods from molecular biology miss. DNA sequencing isn't everything--we need to be able to look at ALL of the biomolecules within an o
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by forgotpwagain 11y ago
A lot of this is front-loaded in the 4 years of undergraduate training, 4 years of medical school, and 4-6 years of residency training that physicians do. Physicians are trained to preload all possible diagnoses based on a certain set of in
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by forgotpwagain 11y ago
I'm curious what the effects of my seeing lots of TV ads during my childhood are. I honestly can't remember specific ads very well, but I'm sure that seeing thousands of soundbites glorifying instant gratification must have h
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by forgotpwagain 11y ago
I will note that Siddhartha Mukherjee is also the author the _The Emperor of All Maladies_, perhaps the greatest popular science book on cancer that is scientifically and historically accurate and very engaging. I highly recommend it (and w
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by forgotpwagain 11y ago
I'm not an expert, but I think there's been a variety of attempts for vascular renormalization--to restore the normal flow of vessels to allow for drug delivery, etc. Rakesh Jain's lab (at MGH) is a big player in this field a
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by forgotpwagain 11y ago
Sure--you won't be able to get every tumor. But there are certain markers that are more common than others, so if you can get the top ~10 done within reasonable measures of safety, you could prevent a nontrivial number of cancers. Ther
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by forgotpwagain 11y ago
The method by which vaccinations work is immunological. I think the most exciting frontier in cancer biology is prophylactic (preventative) vaccination. If we are able to develop effective vaccines against cancers, that will very much chang
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by forgotpwagain 11y ago
In general, blood cancers are more accessible than solid tumors. With blood cancers, the majority of the cancer cells are in the blood or in very well perfused tissues (bone marrow, spleen, thymus, etc), meaning that drugs/treatments c
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by forgotpwagain 11y ago
I seem to recall it being that one's risk of lung cancer due to smoking drops to being very close to a non-smoker's risk after refraining from smoking for 10 years. Other damage is certainly done to the lungs that can cause other
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by forgotpwagain 11y ago
I would argue that the best engineers focus on themselves quite a bit--they just focus on improving themselves and their strengths and weaknesses instead of their relative ranking among others.