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flobosg
searching PlanetScale…
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10 ms
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151.
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by
flobosg
1y ago
The related publication is unfortunately paywalled, but here’s the preprint: https://www.biorxiv.org/content/10.1101/2025.01.16.633462v1
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flobosg
1y ago
See also the many iterations of the Micro Journal: https://github.com/unkyulee/micro-journal
153.
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flobosg
1y ago
I can second the Shoplifters recommendation.
154.
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flobosg
1y ago
> Maybe I'll seriously write the editors a letter regarding this paper. Or put a comment on PubPeer! https://pubpeer.com/publications/ABEC366688EE00BCD774A32A7CC...
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flobosg
1y ago
Earlier discussion from this year: https://news.ycombinator.com/item?id=43492652
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flobosg
1y ago
The show is based on a manga, by the way: https://en.wikipedia.org/wiki/Shin%27ya_Shokud%C5%8D
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flobosg
1y ago
(2021)
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flobosg
1y ago
You just reminded me that I have a SanDisk Clip lying around somewhere in my flat.
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flobosg
1y ago
> Could once is not the same as can predictably first of all I was merely addressing your claim in the previous post. > Second, how can they possibly know this fold isn't actually in the ENTIRE PDB? I doubt very much that the can
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I told AI to make me a protein. Here's what it came up with
(nature.com)
3 points
by
flobosg
1y ago
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0 comments
161.
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flobosg
1y ago
> that probably can't handle truly novel proteins AlphaFold is able to predict novel folds, see https://www.nature.com/articles/s42003-022-03357-1
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flobosg
1y ago
Since Christian Bök’s Xenotext was recently discussed here ( https://news.ycombinator.com/item?id=43974005 ), check out “The March of the Nucleotides”: https://x.com/christianbok/status/10647419109
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flobosg
1y ago
> I honestly can't tell if this is truly clever, like in the way a skilled poet can combine vocabulary and meter constraints to generate wonderful phrases (Kubla Khan poem being a nice example), or just a mechanical process. I can&#
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flobosg
1y ago
In this particular case you can consider codons coding for the same amino acid as synonymous, restricting, as you mentioned, the possible mappings to the ~20 proteinogenic amino acids. Another possibility for expansion would be to take adva
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flobosg
1y ago
Wow! Happy to read that the Xenotext went on. I’ve been following Christian Bök’s work for more than a decade and he never fails to impress me. Ulver’s musical rendition of his “Vowels” poem is just beautiful: https://www.youtube
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flobosg
1y ago
Broadly speaking, think of codon-anticodon pairings, but with actual letters mapped to them. any style of life/ is prim ¦¦¦ ¦¦¦¦¦ ¦¦ ¦¦¦¦ ¦¦ ¦¦¦¦ the faery is rosy/ of glow
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flobosg
1y ago
> the Leidensdruck, i.e. the degree of suffering A literal translation (the pressure of suffering) sounds more meaningful to me.
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flobosg
1y ago
On dwm: xsetroot -name "$(date +'%b %d %H:%M') Focus: $FOCUS"
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flobosg
1y ago
Potatoes are edible batteries! https://www.youtube.com/watch?v=KFDlVgBMomQ
170.
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The Cannae Problem
(joanwestenberg.com)
164 points
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flobosg
1y ago
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106 comments
171.
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flobosg
1y ago
I was living in Chile during its 2010 earthquake ( https://en.wikipedia.org/wiki/2010_Chile_earthquake ). The power outage in my hometown lasted approximately two weeks.
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flobosg
1y ago
Somewhat related: Cuba’s “El Paquete Semanal” – https://en.wikipedia.org/wiki/El_Paquete_Semanal ( https://news.ycombinator.com/item?id=36285363 )
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flobosg
1y ago
Check out his[1] Molecule of the Month series ( https://pdb101.rcsb.org/motm/ ) if you haven’t already! [1]: Although he just retired from it. Janet Iwasa will continue the project.
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flobosg
1y ago
Don’t forget supercomputers! https://en.wikipedia.org/wiki/MareNostrum
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flobosg
1y ago
Base R as well: |> was implemented as a pipe operator in 4.1.0.
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flobosg
1y ago
Previous discussion: https://news.ycombinator.com/item?id=43682686
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flobosg
1y ago
I think the article is quite clear in its explanation. The keyword is retrospectively .
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flobosg
1y ago
The term was coined that year but the actual style exists at least since, well, Windows Aero: https://en.wikipedia.org/wiki/Windows_Aero#Legacy
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flobosg
1y ago
My mind was blown when I read it as a teenager.
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flobosg
2y ago
See also the added soft hyphens within each word for hyphenation: https://practicaltypography.com/optional-hyphens.html#:~:tex...
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