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exratione
searching PlanetScale…
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19 ms
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91.
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by
exratione
12y ago
There are a very few candidate population 3/population 2.5-ish stars that have been discovered in past years, classification based on extremely low metallicity. It would be interesting to see what the spin methodology has to say about
92.
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exratione
12y ago
Reliability theory can be a very useful way to look at many of these things. https://en.wikipedia.org/wiki/Reliability_theory
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exratione
12y ago
Takes all sorts. I put in some time at an office where the team struggled immensely with Ember but found Angular much easier to pick up and produce results with. The scaling thing is just one of the hurdles you have to manage in this framew
94.
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exratione
12y ago
If I'm reading the thesis correctly the modern state top to bottom monopoly on mechanisms of enforcement of common law is a consequence of population growth as it applies to two things, (1) crowd control and (2) attitudes towards metho
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exratione
12y ago
http://news.stanford.edu/news/2007/january17/med-hormone-011... "There is certainly no data out there to suggest that giving growth hormone to an otherwise healthy person will make him or her live longer
96.
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exratione
12y ago
The important thing to realize about the Fermi Paradox is that all generalizations about behavior fail automatically as explanatory theories. It only takes one small group within one species to generate a self-replicating probe, at which po
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exratione
12y ago
There is a tremendously conservative impulse inherent in the way people look at the natural world. The basic assumption for near all discussions is that all change is bad, the exact present situation absent the touch of humanity is good, an
98.
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exratione
12y ago
This is still fairly applicable for the major causes of speed and slowness. https://www.exratione.com/2013/12/considering-speed-and-slow... My impression is that Angular-specific issues are way more important than
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exratione
12y ago
Both obesity and type 2 diabetes are for the vast majority of sufferers voluntary conditions. These people choose to suffer these conditions, and further, every day make the choice again to continue to suffer these conditions. Even very lat
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exratione
12y ago
Counterpoint: the grandmother hypothesis. https://en.wikipedia.org/wiki/Grandmother_hypothesis
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exratione
12y ago
Here are a grab bag of overviews on evolutionary theories of aging, of which there are many, and these don't even cover some of the more recent epicycles, such as explanations for runaway longevity competition in some sessile species:
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exratione
12y ago
Mitteldorf has an interesting take on programmed aging, which is to say the collection of theories suggesting aging is a evolved program that acts to shorten life because there is some very global selection advantage in it. It is worth read
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Progressive Lenses and Large Monitors Do Not Play Well Together
(exratione.com)
7 points
by
exratione
12y ago
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2 comments
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exratione
12y ago
Arguing for a lack of progress today in comparison to half a century ago is simply a matter of not paying attention. Progress today in the fields I pay attention to, e.g. biotechnology and related materials science, is stupendous and accele
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exratione
12y ago
Vaupel is a respected voice in the field. You might look through his publication history. I don't think it's particularly controversial at this point that life expectancy at birth is trending upwards at ~2.5 years/decade and
106.
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exratione
12y ago
Well, sure. Being older is so absolutely amazing in terms of experience, assurance, wealth, power, confidence, and so forth, that all those similar things can actually for a time outweigh the crumbling of your health and your increasing fra
107.
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exratione
12y ago
First, nice to think it'll happen in time for you personally. But it won't unless a lot more people support the right lines of research over the next ten years. That means those based on repair of causes of aging, the well-catalog
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exratione
12y ago
If we define favorite as most often reached for in reference to present discussions, then probably this. People are persistently surprised by the expected results of cumulative gains in all areas of life, here also: http://dx.doi
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exratione
12y ago
The express router array is pretty easy to abuse, it's true. For example, as something you probably shouldn't ever do: https://www.exratione.com/2013/03/nodejs-abusing-express-3-t... I guess the Netflix
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exratione
12y ago
Here's a toy pseudo-random generator I threw together the other day in the course of doing something else: https://www.exratione.com/2014/10/four-word-phrase-pseudoran...
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exratione
12y ago
Not enough, I'd imagine. It has always been a stronger thread in the tech community than elsewhere, but it is still only a thread. Take a survey of your office and you'll find few people who put any thought into radical life exten
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exratione
12y ago
The present outer limits, the very dramatic falloff in survival past age 100, appears to be largely caused by senile systemic amyloidosis, based on autopsy evidence from the recent past. Misfolded proteins, amyloids, clog up your cardiovasc
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exratione
12y ago
It's amazing how much goes to line the pockets of politicians and their cronies, and with the flimsiest of expected outcomes on the part of those who give, in an age in which creating actually worthwhile things, new technologies and sc
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exratione
12y ago
It's amazing the stuff that gets funded in the research community in place of, you know, actually addressing the physical, biochemical causes of aging.
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exratione
12y ago
People overestimate the state of medicine with respect to autoimmunity, which is funny in a way because they are largely completely in the dark as to how fast medical research is moving in all fields, and think that many types of near futur
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exratione
12y ago
There's always knowledge to be gained from comparative biology. But there's knowledge and then there's applicable knowledge. I think the odds of finding anything that can be ported to humans as a therapy or enhancement on a s
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Rejuvenation Biotechnology: Toward the Indefinite Postponement of Menopause
(sens.org)
1 points
by
exratione
12y ago
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0 comments
118.
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exratione
12y ago
Aging is a global phenomenon of damage accumulation throughout the body: more damage means faster aging. People who show more damage in any one measure tend to show more damage in all the others too, as it all stems from a few root causes.
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exratione
12y ago
You don't need to crowdfund any more than it costs to convince a group with $1bn that they can make money on this by spending that to commercialize your demonstration. That is often just a few million, or even less, depending on how co
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exratione
12y ago
This displays a profound ignorance of the real situation, which is that the majority of useful early stage research is funded by philanthropy. Not by government, not by companies, but by people making donations. It doesn't come from th
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