epistasis

5 ms·

91.
by epistasis 2mo ago
Even taking you at your word, immigrants also create far more jobs. The economy is not some zero sum thing, with some fixed amount of jobs and fixed amount of work and fixed amount of wealth to be split. Every economic analysis I have ever
92.
by epistasis 2mo ago
How, in any way does this help the wellbeing of a citizen? Why bring up that very strange point, which is completely unconnected to the massive harm here. If anything, these policies harm the citizens of the US in a myriad of ways. There&#x
93.
by epistasis 2mo ago
If they have paid into it like anybody else, crucially. They met their responsibilities.
94.
by epistasis 2mo ago
What responsibility does a non-citizen shirk? They must follow lows, pay taxes, etc. Even for things like social security. I sometimes wonder where these concepts come from, because it sounds like somebody tricked you into thinking that non
95.
by epistasis 2mo ago
Yes, the side effects were very extreme. As time goes on, I'm optimistic that management of the side effects will improve, and outcomes will improve along with that too. Much like chemotherapy, this type of treatment affects a lot of n
96.
by epistasis 2mo ago
Metastatic pancreatic cancer is the first indication for this class of RAS-inhibitor, but it certainly won't be the last, and it seems certain that there will be many many more cancers where this drug gets approved. There are mutations
97.
by epistasis 2mo ago
I do use US Mobile, and I recently switched to it because T-mobile made it so difficult to pay a bill, it was nearly impossible to get them to accept money. And a ~decade ago in SF I did have Sonic 1Gbps symmetric fiber for something like $
98.
by epistasis 2mo ago
> a 5G SIM with unlimited data (something you can get for 10/15 euros a month) is cheaper than a fiber connection (that starts from 25 euros). These sorts of prices are unheard of in the US, so incredibly low. Something has gone dee
99.
by epistasis 2mo ago
Tell me more about this. I've yet to find a good summary! It happens here in California with PG&E with fire prevention money and infrastructure money; the executives declare victory early having spent a fraction of the allocated fu
100.
by epistasis 2mo ago
In SF they burn stuff on the streets to prevent any change to the physical structure. No new apartments, no new infrastructure allowed.
101.
by epistasis 2mo ago
It's so funny to see FP4.... I remember 20 years ago being asked what sort of HPC we needed in genomics, and the answer was basically, "lower precision, faster" for the stuff I was working on. But FP4 is, well, almost comical
102.
by epistasis 2mo ago
This is so stupid. It's really hard to understand how such utter moronic behavior even gets proposed. The best comparison I heard for the cultural idiocy is that it's like asking for the US to end SEC football. And ending French l
103.
by epistasis 2mo ago
Telescope design, funding, and construction is a long long process, longer than any administration, and there are some truly wonderful telescopes coming online right now. The Nancy Grace Roman telescope is scheduled to launch in 9 days, on
104.
by epistasis 2mo ago
They do this mostly with spectroscopy, breaking out the light by frequency. The longer the light has been travelling, the more frequency shifts into redder frequencies, because the universe is continually expanding. But those distances are
105.
by epistasis 2mo ago
Yeah, exactly, the thinking process of the latest Claude models have really mucked up the responses they show to users, presumably to game benchmarks or something. My agents are constantly referring to things that happened behind the scenes
106.
by epistasis 2mo ago
Pi with Claude is better than Claude code in my experience. But I even use old GLM5.2 with pi and generally have a better experience than current Claude Code. It reminds me of peak productivity with Claude Code of 5+ months ago.
107.
by epistasis 2mo ago
Claude Code is quickly becoming an anchor. Every week I marvel at how much worse it gets, how much more essential information is hidden and replaced with bloated useless TUI and rambling tangential responses that hide the useful bits of inf
108.
by epistasis 2mo ago
I think the "expected value" was priced in, but regardless of the result, this trial would move the stock price towards that direction. Biotech is one of the very very very few areas of the stockmarket where specialist knowledge g
109.
by epistasis 2mo ago
"Polarizing" is a word that kind of applies, especially if one is trying to be polite, but really it's one of the most politically disinformed issues in a long long time. A bunch of grifters pushed fear, uncertainty, and doub
110.
by epistasis 2mo ago
Ever since I first heard of them a decade ago, it seemed that mRNA therapeutic vaccines were going to be the next wave of massive improvements in care. It's taken a bit longer than I had expected, and it's not that mRNA is the on
111.
The Hugging Face Hack (Hoog Video)(youtube.com)
3 points by epistasis 2mo ago|0 comments
112.
by epistasis 2mo ago
Just wait until people hear about the temperature increases caused by parking lots....
113.
by epistasis 2mo ago
Yeah, same here. Shopping on Amazon is awful. Logistics and delivery, A-OK, but I don't want what they are selling. I'm happy to wait 3 more days, and have inaccurate delivery estimates, in order to get what I actually want. It al
114.
by epistasis 2mo ago
I first heard of the connection between breast cancer rates and performing use more than a decade ago, and it took a lot to convince me it was true, but a lot of it was seeing the connection the the insulin receptor protein. Here they find
115.
by epistasis 2mo ago
Claude's RLHF has gone really over the top in recent versions. If you browbeat Claude enough you can get it to start self-censoring, but it takes a lot of training and memory creation. I almost feel bad for it, given the amount of brow
116.
by epistasis 2mo ago
I've been very happy with forgejo for a personal, private server. I don't care much about the social aspects of GitHub, but I do care a ton about hosting code for long periods of time, long after I've completely changed my pe
117.
by epistasis 2mo ago
> An expansion that has almost nothing to do with the rest of the ACA. That's a very strange assertion, it's literally "the ACA medicaid expansion" and was a key part of the whole thing. I'm saying most political
118.
by epistasis 2mo ago
ACA has saved tons of lives. Due to the intense opposition, it was not structured in a way that could save money, but rather structured in the way that it could get through congress. Additionally, as somebody who was around pre-ACA, I can n
119.
by epistasis 2mo ago
That's not what I was saying. The foundational research that built the massive economic engine of the current US did not come from industrial research.
120.
by epistasis 2mo ago
Even Bell Labs would not be doing the type of research that is necessary. Look at all the innovation in science that happened back then! Bell Labs was an outlier but it was not the primary driver of science by any means.

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