djur

10 ms·

151.
by djur 2y ago
Losing weight makes "walking a lot" achievable for many people.
152.
by djur 2y ago
Why is your preferred set of professionals better than another? Do you have research showing that treating obesity as a substance abuse disorder has positive outcomes?
153.
by djur 2y ago
A professional such as a doctor, who prescribes a medication that helps address the issue?
154.
by djur 2y ago
I agree, but I also think that in most cases people are more likely to be able to transition to an active, healthy lifestyle with moderate eating if they have help taking weight off. Being heavy makes exercise painful, exhausting, and often
155.
by djur 2y ago
As far as I know the pharmaceutical companies have not adopted a strategy of attempting to undermine or block surgical treatments, which you'd expect if their operating strategy was as you say.
156.
by djur 2y ago
Intermittent fasting is different than calorie restriction. There are calorie-restricted diets where you eat small amounts constantly throughout the day (this used to be the go-to recommendation of doctors). Intermittent fasting doesn'
157.
by djur 2y ago
Yeah, because there's a (previously observed) paradoxical effect where decreasing blood glucose levels can accelerate the progress of diabetic retinopathy.
158.
by djur 2y ago
In any case, long-term obesity leads to (and is worsened by) decreased exercise, which results in decreased bone density and muscle loss. There might be an argument for avoiding GLP-1 agonists for slightly overweight people, but for obese p
159.
by djur 2y ago
There's a lot of information you can find if you spend some time to do the research before making declarations on the topic, but studies have shown significant reductions in alcohol consumption, for one thing. Anecdotally, multiple peo
160.
by djur 2y ago
"Availability of hyperpalatable foods" and "urge to eat hyperpalatable foods to excess" are both prior causes to "eating hyperpalatable foods to excess", even if neither of them are a root cause (and I don&#x27
161.
by djur 2y ago
There have been long-term studies of semaglutide much longer than a year. I'm not aware of any finding that indicates that long-term use should be avoided. There is some indication that the weight loss plateaus within the first several
162.
by djur 2y ago
Your own personal experience is not a "source" for what is easy, hard, possible or impossible for other people.
163.
by djur 2y ago
> probably well beyond the published ones What is this claim based on?
164.
by djur 2y ago
Anecdotally, the people I know who have been taking GLP-1 agonists have not been following eating patterns consistent with "intermittent fasting". They're just eating less (especially snacking).
165.
by djur 2y ago
It's insider trading. I'm not sure if you're trying to defend him by comparing him to other con artists?
166.
by djur 2y ago
I think a lot of programmers love the idea of being game developers but don't really have much of an idea for what to make, so they get diverted into developing a game engine or even tools to support a game engine instead. People can s
167.
by djur 2y ago
There's something ironic about condemning someone for "ascetic renunciation of pleasures such as guis" and publishing it as a Markdown file available only by cloning a git repo.
168.
by djur 2y ago
I'm not sure where the weight behind his opinions comes from, though. Braid and The Witness are both well-respected games, but they're respected from a game design perspective, not as technical accomplishments. If you told me that
169.
by djur 2y ago
Apparently only 13 of them are actually new levels. 12 are alternative versions of existing levels and the rest are "commentary index levels".
170.
by djur 2y ago
Yeah, I'm not a big fan of Blow, but this clearly wasn't just a cash grab -- it sounds like a decent amount of time and money went into the remaster. I think it's fine for him to be personally upset that it didn't do bet
171.
by djur 2y ago
It's a legendary indie game in part because everybody played it. It was in the Humble Indie Bundle 2 in 2010, which means its market value approached "free copy in a Cracker Jack box" at that point. Braid 2 might have sold be
172.
by djur 2y ago
Making a demo of a single level of a commercial game was a pretty common way of showing off what the HTML5 canvas could do, but I remember people basing it on stuff like Doom, where you're less likely to get sued by an angry game dev.
173.
by djur 2y ago
Blow has a reasonably large audience as a game dev thinkfluencer. I think he might have overestimated what % of a Twitch or YouTube audience is willing to go actually pay money for commentary from the same person.
174.
by djur 2y ago
The market for games is just radically different than it was in 2008. Braid had very high production values and a reasonably low price tag at a time where "quirky indie 2D puzzle platformer with interesting aesthetic and a mystery&quot
175.
by djur 2y ago
Singular "they" was more controversial at the time and was considered ungrammatical by some. "She" is unquestionably grammatical and yet it seems to be persistently shocking for people to read. (I would prefer "they
176.
by djur 2y ago
Infocom games were adventure games, just text adventures. The tricks in Hitchhiker's are fun but not really great for playability. The Interactive Fiction community has spent the last few decades trying to figure out ways to get that s
177.
by djur 2y ago
US military used to be largely made up of state militias (dating back to colonial days), run by the governor, with the federal government sometimes funding, equipping, and mobilizing those militias in times of war. Commissions in state mili
178.
by djur 2y ago
Archipelago also supports multiworld with the same game, which I suppose might seem obvious but hadn't occurred to me until I saw multiworld co-op races with the Final Fantasy VI randomizer Worlds Collide -- two teams of two, both team
179.
by djur 2y ago
From the same book, the "it is our suffering that brings us together" passage has burned itself into my mind and has often been a comfort in dark times. I can't imagine finding it impersonal or robotic. Frank and unadorned, p
180.
by djur 2y ago
My understanding is that it's more about mitigating risk than avoiding an association with eugenics. If the gene therapy has unforeseen consequences the harm is multiplied with every generation and is harder to address once found.

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