directevolve

10 ms·

31.
by directevolve 9mo ago
The Interventions Testing Program is the closest thing I know of along these lines. “ The Interventions Testing Program (ITP) is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice. Investigators
32.
by directevolve 9mo ago
Low dose extended release Adderall. I feel completely myself. It helps me make conscious choices about transitions between tasks. I don’t get irritated by interruptions. When I transition, it’s easier to put down what I was doing before and
33.
by directevolve 9mo ago
I had no trouble running Ubuntu on my ASUS Vivobook 4 years ago.
34.
by directevolve 9mo ago
Yep. Bad use of force by police is tragic, but it’s happened before and will happen again. This is federal support for murdering liberals.
35.
by directevolve 9mo ago
For the next elections, we need to convince swing voters and inconsistent voters to turn out for Democrats next election. Not reprogram the terminally MAGA. The next onion layer will be credulous Fox viewers. But I’m even less clear on how
36.
by directevolve 9mo ago
And in this case, shooting her made the situation much more dangerous. It caused her dead foot to stomp the gas pedal, dangerously accelerating the car uncontrollably until it crashed on the side of the road.
37.
by directevolve 9mo ago
Vaccine studies use a different experimental design known as “longitudinal,” meaning they follow people over time. This study did not do that. It’s still a valid design, just limited in what it tells us.
38.
by directevolve 9mo ago
As there were no healthy controls or comparison with blinded radiologist performance, it is not possible to answer those questions using this study. The point was to evaluate AI sensitivity, which is useful. However, without healthy control
39.
by directevolve 9mo ago
You can now see a very clear picture of exactly where that cop was standing with respect to the car as he drew his gun on the front page of the New York Times. He was not in the path of the car. And there was no reason for him to walk up an
40.
by directevolve 9mo ago
Police were shouting contradictory instructions at her, including to move her car. Her car had hardly starting to move when the cop walked around the front of the car and leaned in the window to shoot her in the face. Her corpse’s foot was
41.
by directevolve 9mo ago
I was just reinforcing that point as your comment was worded in a way that left room for doubt. Sorry if this came across as critical toward you or implying you held a different interpretation.
42.
by directevolve 9mo ago
No, this design is not capable of showing this. It did not compare to unblinded humans, did not provide AI with the same data used to make the initial diagnosis, and did not include healthy controls. It measures sensivitity only.
43.
by directevolve 9mo ago
There were no healthy controls, so they can only measure sensitivity, not specificity in this design.
44.
by directevolve 9mo ago
In case you missed it, they weren't using AI to make these diagnoses.
45.
by directevolve 9mo ago
The did NOT test radiologists. There were NO healthy controls. They evaluated AI false negative rate and used exclusively unblinded radiologists to grade the level of visibility and other features of the cancer. Utility of the study is to e
46.
by directevolve 9mo ago
The point of this study is that it suggests that fully AI-automated mammography can currently deliver 70% sensitivity in detecting breast cancer using this model. It does not enable us to compare AI to unaided human performance. As this stu
47.
by directevolve 9mo ago
Yes, CRISPR’s mentioned in the article. Someone should write a book about it to break down the history leading up to this accomplishment.
48.
by directevolve 9mo ago
Well, CRISPR-Cas9 as a tool for genetic engineering was only invented in 2012. A 13-year translation timeline is not unusual, maybe even unusually fast. CAR-T cell therapy for cancer took 30 years from discovery to clinic. It took about 30
49.
by directevolve 9mo ago
I think it’s worth addressing this with more nuance. Companies can get a METHOD-OF-USE PATENT (MOU) on an old drug for a new INDICATION. This gives them the exclusive right to LABEL AND MARKET that drug for that indication for a period of t
50.
by directevolve 10mo ago
That’s an understandable misreading of what she said. I appreciate that the rhetorical effect could feel like a sly way to slip in asymmetric gender standards about how to interpret divorce. But I am a pedantic person who prefers to focus o
51.
by directevolve 10mo ago
The important point here is that you can become much more effective by cutting wasted activity. Wasted motion and power saps your time, energy, and motivation. It obscures your vision. It creates unnecessary risk. It decreases your awarenes
52.
by directevolve 10mo ago
A good depiction of the gritty realities and the meaning of material striving for the very poor in turn of the century farm life is the novel Independent People, by Halldor Laxness, an Icelandic nobel laureate.
53.
by directevolve 10mo ago
This is a wildly disingenuous interpretation of that study. “ Using transaction-level data on US congressional stock trades, we find that lawmakers who later ascend to leadership positions perform similarly to matched peers beforehand but o
54.
by directevolve 10mo ago
> Montreal probably has the most restrictive rent control in Canada but it's also seeing the strongest apartment development growth A wonderful city like Montreal can drive enough demand for housing to overcome red tape, and still b
55.
by directevolve 10mo ago
If most successful entrepreneurs are from ordinary backgrounds, one explanation is that most entrepreneurs, successful or unsuccessful, are from ordinary backgrounds. Another is that wealthy families might be pushing kids into entrepreneurs
56.
by directevolve 11mo ago
That’s a statement of fact, but not intrinsically a problem. Being alive changes your brain chemistry.
57.
by directevolve 11mo ago
The study found the average effect was no different from placebo. It’s plausible, based on anecdotes like the one you’re responding to, that Prozac is harmful for some people, helpful for others, with the expected benefit close to zero. If
58.
by directevolve 11mo ago
This isn’t the whole story. I’ve been driving the same Prius compact since 2015, and only I the last few years have I suddenly started experiencing these insanely bright headlights. The giant cars have been around the whole time. The bright
59.
by directevolve 11mo ago
Charity navigator quantifies overhead. EA tried to quantify impact. To understand the difference, consider two hypothetical charities. Charity A has $1 million/year in administrative costs, while charity B’s costs are only $500,00&#x2F
60.
by directevolve 11mo ago
This is historically inaccurate. EA’s origins are in charity evalutions to quantify the marginal impact of a donation. This motivated philosophical debate about how to operationalize “good,” and later became influential enough to have polit

More ›