david_l_lin

11 ms·

61.
by david_l_lin 6y ago
Each microbiome is unique, and preventive measures against bacteria that cause gum disease may not be effective against bacteria that contribute to cavities and vice versa. The solutions (such as prescription-strength fluoridated toothpaste
62.
by david_l_lin 6y ago
Great questions! We implement a host-depletion step in both the wet lab, to increase sequencing depth of the microbiome, and dry lab. You may be concerned about potential bias introduced, and we've done some extensive research with our
63.
by david_l_lin 6y ago
That's a great suggestion, we'll work on getting this added to our list of FAQs.
64.
by david_l_lin 6y ago
Short of giving away some of our secret sauce and analysis pipeline, what we do is sequence the nucleic acids in your saliva in a de-identified fashion such that only Bristle scientists can match your sequence data with any potential identi
65.
by david_l_lin 6y ago
Our early access test is recreational. However, we anticipate to provide clinical decisions for oral health in the near future. By signing up for the educational test today, you are also contributing to scientific discoveries and helping to
66.
by david_l_lin 6y ago
Thank you for your input, that's completely understandable. We're describing in our website the product that is undergoing clinical validation, but want to provide consumers an opportunity to gain insight into their oral microbiom
67.
by david_l_lin 6y ago
Thanks for catching that! We'll get it fixed right away!
68.
by david_l_lin 6y ago
This is a great question! We are actively looking into circadian oscillations of the oral microbiome, but don't currently have any recommendations around specific times for sample collection. The same goes for intermittent fasting! We
69.
by david_l_lin 6y ago
For our early access product, we will be providing you your comprehensive microbiome profile, how you compare to other users, and relative oral health scores. We also provide a summary of current literature around a number of key microbes i
70.
by david_l_lin 6y ago
We maintain the key and will never share it without your consent. The key is critical to reporting microbiome data back to the correct person. Additionally, maintaining these identifiers will be crucial when we plan to add additional health
71.
by david_l_lin 6y ago
HIPAA applies to any circumstance around handling PHI. We handle your self-reported survey data, and microbiome data as PHI. We do NOT have to be a "covered entity" to apply HIPAA compliant protocols to our data handling. It'
72.
by david_l_lin 6y ago
We self-impose HIPAA complaint protocols despite not being a covered entity. The answer to the question: "Is customer data protected by HIPAA?" is essentially the same. 1. Any data that can be considered PHI (survey data, medical
73.
by david_l_lin 6y ago
You can find our response above. Thank you for your patience, and for the engaging discussion!
74.
by david_l_lin 6y ago
Absolutely, you may request that your physical sample be destroyed after receiving your results. At present, we biobank samples in the event that the sample needs to be re-run. Please send us an email at info@bristlehealth.com and we can en
75.
by david_l_lin 6y ago
This is a great question! In short, there is a network effect with our platform. Each sample we sequence contributes to a database of novel bacteria, viruses, and fungi that we can use to discover new microbes.
76.
by david_l_lin 6y ago
I completely understand your hesitation around the anonymization of data, and will have more detail around how your data will be anonymizes and used on our website shortly.
77.
by david_l_lin 6y ago
Apologies for the lack of clarity! I can’t make any immediate guarantees around sending our kit to Australia. However, we do not collect payment until after we ship the kit, so please sign up on our early access page to hold a spot in line.
78.
by david_l_lin 6y ago
I can’t make any immediate guarantees around sending our kit to Europe. However, we do not collect payment until after we ship the kit, so please sign up on our early access page to hold a spot in line. If/when we reach critical mass w
79.
by david_l_lin 6y ago
Our core technology is based around the oral microbiome for a number of key reasons. 1. decades of research have shown causal relationships between the oral microbiome and preventable gum disease. 2. the oral microbiome is much lower in di
80.
by david_l_lin 6y ago
I'm 90% sure we can do CAN. Sign up for early access through our website: bristlehealth.com, and we'll reach out when your kit is ready!
81.
by david_l_lin 6y ago
Bristle CSO here. To elaborate on Esyir's reply, through saliva collection, we inevitably will have your DNA in the sample. However, our analysis selectively removes host DNA from the sample, enabling targeted sequencing of the oral mi
82.
by david_l_lin 6y ago
See Esyir's response. In short, we do NOT look up your DNA, and only look into microbial DNA. In fact, we do a host depletion step to enrich for microbial DNA prior to sequencing, then a following host depletion step prior to microbial
83.
by david_l_lin 6y ago
If only we were that clever
84.
by david_l_lin 6y ago
Thank you for participating! Co-founder and CSO here. Thanks for the feedback regarding the website, we're in the process of updating the page to improve its layout. We absolutely will not be selling your microbiome data without your c
85.
by david_l_lin 6y ago
At the moment, we don't account for circadian rhythms. As we explore some of the insights to the oral microbiome, that's definitely one of the avenues we'd love to dig into. We do ask customers to fill out a relatively detail