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daemonk
searching PlanetScale…
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181.
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daemonk
9y ago
Blizzard should put in an AI-assisted play mode where players are limited to X lines of code that can be launched with keyboard commands.
182.
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daemonk
9y ago
Did he actually cite any scientific literature? I would be interested in reading them. If not, then they are just intelligently dressed up assumptions.
183.
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daemonk
9y ago
You should read up on cryptic mutations. I don't think it is that popular in the evolutionary biology field though, mainly because it can be a very vague mechanism.
184.
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daemonk
9y ago
I've just started working remotely. I think one of the major benefit for me is actually that we mostly communicate via e-mail/messaging services. Of course there are plenty of situations where talking face to face is more informat
185.
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daemonk
9y ago
This is a great blog post response to the article: https://medium.com/@GaetanBurgio/should-we-be-worried-about-...
186.
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daemonk
9y ago
Title is a bit dramatic. People just need to choose their gRNAs better based on available genomes.
187.
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daemonk
9y ago
Do ratings agencies like Moody self sustain on the psychology of the people who listen to them? People who take them seriously factors them into their decisions. People who don't take them seriously has to still factor them into their
188.
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daemonk
9y ago
Based on what I can gather from the data model, this would be great for categorical type data where there are a limited amount of categories for each event? Would this be fast for querying quantitative data where values might be unique?
189.
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daemonk
9y ago
I think the argument is that certain services warrant a faster internet pipeline. Doctors performing remote surgeries, scientific collaborations, emergency services...etc. But the problem ultimately comes down how to make the distinction be
190.
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daemonk
10y ago
If someone thinks the peak of their creativity and mental abilities occurs at mid 20's, then I feel sad for them. It's more about attitude and practicalities of life than an inherent degradation of mental faculties. As someone who
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daemonk
10y ago
So this is really just a smart caching system for slower hard drives?
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daemonk
10y ago
I work in bioinformatics. I remember writing a rough implementation of this for the human genome during my phd as a way to compress sequence information. Turns out it doesn't perform better than gzip.
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daemonk
10y ago
I think the author of the post was trying to say that he has disproportionally allocated his time from finishing projects to just learning new things. There needs to be a good balance between keeping up to date with technology and producing
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daemonk
10y ago
I understand there is a technical aspect of how long you keep the files. But the end users probably don't really care. When I use a service like this to transfer a file to someone else, I would like to be able to write a message to the
195.
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daemonk
10y ago
Nice. This is the more interesting market for AMD rather than the gaming market in my opinion. 128 PCIe lanes and up to 4TB of ram will be awesome.
196.
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daemonk
10y ago
I like it. But I would like a more concrete answer to how long the files are kept. "As long as possible" is not really a great answer. I don't expect it to be there indefinitely, but something like "For at least 5 days.
197.
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daemonk
10y ago
I am not a power user. But I found this to be a great read. It's interesting to see the historical and sometimes vestigial traces in unix. However, for all the flaws that were pointed out, I still can't imagine doing my work on wi
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daemonk
10y ago
I am looking forward more to their Naples cpus for servers.
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daemonk
10y ago
I think one of the important points the story tries to make is the way we perceive/react to the idea of free-will vs destiny is very anthropomorphic because we have sequential consciousness. The heptapods have simultaneous consciousnes
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daemonk
10y ago
Doudna definitely deserves all the credit for clarifying the mechanism and modifying the system for sgRNA instead of the original two RNAs. But what Zhang did was not trivial. He did not just take Doudna's system and threw it into a ma
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daemonk
10y ago
One interesting thing about what they did was they assayed potential insertion sites with ChIP-seq to see how much off-target effects there are. They used a catalytically inactive cas9 for IP to see the quantity and strength of off-targets.
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daemonk
10y ago
It's all a matter of perspective and how you interpret numbers. I can also say: "15% is standard surplus according to regulation, but California is generating 40% (6/15) more than the standard surplus". Now that seems li
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daemonk
10y ago
Yeah some kind of slow incremental behavior shift towards something would be more insidious. Maybe allow the user to define a rotating theme of the week. This week I like dinosaurs, so the plugin will slowly ramp up dinosaur related behavio
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daemonk
10y ago
Can someone make a browser plugin that will send fake data to facebook? Instead of hiding your own behavior, might as well poison their database.
205.
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daemonk
10y ago
Seems like a lot of these historical incidents are being brought up recently. They are certainly interesting and perhaps show that humanity as a whole tend to repeat the same actions. But is it also the goal to attempt to justify the curren
206.
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daemonk
10y ago
Sure. But the question assumed that the physical length can be variable depending on the environment. Even if that was the case, measurement of telomeres by the sequence themselves will be independent of environmental factor. Maybe this is
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daemonk
10y ago
Telomere length is not measured by physical length. It is measured by the actual number of repeats of the sequence.
208.
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daemonk
10y ago
tldr for biologists out there. They made a transgenic mouse line of doxycycline inducible Yamanaka factors in progeria (LAKI) background. Too high induction lead to mortality and teratomas, which is known. They cyclicly induced the Yamanaka
209.
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daemonk
10y ago
Tert has been shown to have non-canonical functions interacting with signaling pathways (wnt and nf-kb). It's easy to think of genes as a single function entity when the truth is a lot of genes have pleiotropic effects. The same can pr
210.
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daemonk
10y ago
I kinda agree in the sense that I think that a lot of the tech jobs out there are not "difficult" in a way that requires years and years of experience to perform reasonably well at. So maybe someone older should look for jobs that
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