cthalupa

35 ms·

391.
by cthalupa 1y ago
Lowering LDL is one of the best preventative measures we have for ASCVD. https://www.lipidjournal.com/article/S1933-2874%2825%2900317... That people can still experience a heat attack even with low LDL does not change
392.
by cthalupa 1y ago
How are you going to split the country up? Because it certainly doesn't make sense to do it by state. Rural California is as conservative as urban Texas is liberal.
393.
by cthalupa 1y ago
It's not even a matter of calling people fascists or nazis - there's been plenty of violence towards the politicians on the opposite side of the aisle, too. Nancy Pelosi and her husband. Melissa Hortman, John and Yvette Hoffman ea
394.
by cthalupa 1y ago
All you have to do is look at all of the impositions that republican administrations and politicians have placed on USPS and the heaps of denigration they've piled on it to see the truth of the matter. From forcing them to fund all fut
395.
by cthalupa 1y ago
Except what the government purchased is a block of non-voting shares as long as the government holds them. So what benefit does that provide over grants?
396.
by cthalupa 1y ago
But they don't get to take part in the decision making with this equity stake either. The shares are non-voting while the government holds them, and revert to voting shares once sold to a private entity.
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by cthalupa 1y ago
Police training academy is already generally considered to be insufficient, which is part of why cops continue to receive so much ongoing training as part of the job. Getting a few rushed bootcamp style classes is not going to do anything t
398.
by cthalupa 1y ago
The Royal Marechaussee is 1/10th the size of the National Police Force and as you noted have quite specialized tasks. They are not the people handling day to day crime and interactions with civilians for mundane police actions. They al
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by cthalupa 1y ago
Gun smuggling is not the kind of crime that national guardsman standing around looking menacing stops. This is the sort of work detectives and specialized units do. Specialized surveillance, physical and digital, informants, etc. People tak
400.
by cthalupa 1y ago
There are 1.21 firearms for every person in the USA. There are .15 for every person in Europe. If you don't understand how having 8x the number of firearms per capita increases the ease in which criminals have access to them, I'm
401.
by cthalupa 1y ago
His point is that the crime rate being lower in these places does not happen due to them having militarized police, so assuming that militarized police in general, much less literally using the military for policing will drop the crime rate
402.
by cthalupa 1y ago
Losing weight through any method will make your metabolism slow down - fat is metabolically active. Uncouplers won't change this. Even if 100% of your weight loss is fat, your BMR is going to drop. The amount of metabolic adaptation fr
403.
by cthalupa 1y ago
I'm sure it is the default stance for some. Many is hard to quantify. In my experience it is not the majority, nor is it a stance that makes much sense to me in general.
404.
by cthalupa 1y ago
For more than half of my life, I was quite skinny. I was not exhibiting any particularly strong willpower or self control. I never had to put forth any effort in not being fat. It was not a struggle, it was not a challenge, and it was not b
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by cthalupa 1y ago
> Eventually you'd want to come off the drug, right? When that happens, you would need to do just this. I've made enough changes to my lifestyle that I am confident I could come off the drug and maintain the lost weight. I&#x27
406.
by cthalupa 1y ago
I would agree, personally - I won't go near DNP, and even the newer stuff like BAM15 that is supposed to be incredibly selective I am quite suspicious of. But you still see people losing tons of weight on GLP-1s wanting it to go faster
407.
by cthalupa 1y ago
> I’m now beginning to question if it’s closer to a weird vitamin that we face a systemic deficit of. There's some studies suggesting that a big part of what influences someone to naturally be fat or skinny is tied to natural produc
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by cthalupa 1y ago
I really don't understand this skepticism around semaglutide and long-term effects. One, GLP-1s are not a new class of drug. We have had them in various forms for about two decades now. Two, the clinical trials have followed the standa
409.
by cthalupa 1y ago
Yes, there are a variety of organizations that are attempting to propagate the idea that you can be healthy at any size. Which, as a formerly obese person, I knew was a load of bullshit even at my fattest. I don't know if anyone actual
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by cthalupa 1y ago
It's not the precursors, it's the freeze dried powder form of the drug plus an excipient, generally mannitol. You just reconstitute it with BAC water and inject it.
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by cthalupa 1y ago
The studies for Reta are showing gangbusters results. And it's being developed by Eli Lilly, so they hardly need funding. I swapped to Reta from Tirz and have found it to be a significantly better option myself.
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by cthalupa 1y ago
These hormones occur naturally in the body. We found an analog in nature that behaves a bit differently in that it is longer lasting. Now we have synthetic versions based on that understanding. And the gila monsters have their own circulati
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by cthalupa 1y ago
A huge chunk of Novo losing it's valuation is the fact that Eli Lilly is absolutely destroying them on the next generations of these. Tirzepatide is better than Semaglutide, and Retatrutide is better than Tirzepatide. Mazdutide looks t
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by cthalupa 1y ago
I've dropped about 1/3rd of my bodyweight on retatrutide. The 2nd most common comment I receive is that I look 5+ years younger.
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by cthalupa 1y ago
Not universally. Pitavastatin has a variety of beneficial effects on mitochondria and seems to have far more minimal impact on the CoQ10 pathway that some statins inhibit.
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by cthalupa 1y ago
Except the post they responded to specifically called out HIV-associated lipohypertrophy and the post you are responding to pointed out that the issues being tackled are not unique to HIV-associated lipohypertrophy. More than 70% of America
417.
by cthalupa 1y ago
Correlation is not causation. Plenty of people theorize there is large selective advantage here, sure. They may even be correct! Others disagree with them on it being a large advantage. But even if there is it doesn't mean that there i
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by cthalupa 1y ago
None of which addresses the point. Combating all of those urges and changing your habits via willpower is still far more difficult than a weekly injection that provides huge help in combating said urges.
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by cthalupa 1y ago
But you also take up resources, continue to decline physically, etc. We know that there is strong selection pressure for things that occur during reproductive years. No one debates this. How much the sort of scenarios you're discussing
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by cthalupa 1y ago
This is such an absurd statement. If changing your habits was much easier then we wouldn't need these medications and the world wouldn't keep getting fatter. People have known how to not be fat for a long time, yet the obesity rat

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