comicjk

18 ms·

151.
by comicjk 6y ago
In my experience, not quite as fast for fully-tuned code, but the difference is small - and given the same project deadline, the PyTorch version will probably be faster.
152.
by comicjk 6y ago
It's also a lot of fun. For anyone that likes math, but also likes weird approximations, there's all kinds of juicy stuff in scientific computing. It will make you a better ML coder, too.
153.
by comicjk 6y ago
"Non-linear" threw me off for a second - I almost never see the mathematically correct definition of linear in computer science spaces. For anyone wondering, Celsius to Fahrenheit is an affine transform, technically not linear, be
154.
by comicjk 6y ago
I work at Schrodinger Inc, collaborating with the people who make TorchANI ( https://aiqm.github.io/torchani/ ). This currently predicts only molecular energies in the public codebase, but I expect they will add electron
155.
by comicjk 6y ago
Density functional theory is still quantum mechanics, but operating on the expected electron density itself, rather than the many-body problem of all the electrons. It's pretty good, but not fast - around a CPU-minute for a medium-size
156.
by comicjk 6y ago
Trying to predict where electrons go in a molecule, but using a classical model. This can be done with supervised machine learning - you can use quantum mechanics to get lots of labeled data - but it's a tough problem, because chemical
157.
by comicjk 6y ago
The company that provided the data, Surgisphere, might have been trying to raise their profile by getting a big publication. They're a bit shady. https://blogs.sciencemag.org/pipeline/archives/2020/06&#x2
158.
by comicjk 6y ago
Oil deposits are permeable rock with a mix of oil and water in the pores. Pumping oil down into such a formation would be slow and expensive. It would also take different equipment from that which is there at the wellheads now, so you could
159.
by comicjk 7y ago
Existing vaccine efforts will probably succeed, but the possibility that they fail is real and quite scary (to me, anyway). So I'm glad we have a bunch of longer-term speculative projects as backup.
160.
by comicjk 7y ago
Just because people are out and about doesn't mean we have to go back to the old value of R. In order to make easing lockdown viable, we need to reduce R for people outside, in every way we can afford. Masks for everyone, of the highes
161.
by comicjk 7y ago
I agree with everything here except the reference to QE. Quantitative Easing works to control the money supply only because the central bank can quickly mop the money back up by selling the bonds it previously bought. The central bank can&#
162.
by comicjk 7y ago
What about a more visual description, like "safety circle"? When I was a Boy Scout learning to use an axe, they called the danger zone within reach of the axe the "blood circle". A bit overwrought, but it certainly stuck
163.
by comicjk 7y ago
There are a few computational drug discovery companies that might suit you. For example, I work at Schrodinger, whose motto is "Fight Disease With Code." https://www.schrodinger.com/careers But you're right t
164.
by comicjk 7y ago
I agree that public health authorities have not lied, but that's not the point. "Would transmission be reduced if everyone wore a mask?" is exactly the kind of question public health authorities should be asking! The answer s
165.
by comicjk 7y ago
They should have been developing more than one test anyway. This reduces the risk of failure, and if you get multiple working tests, it allows some cross-checking to reduce false results. Failure to diversify is also mismanagement (though c
166.
by comicjk 7y ago
Here's a short paper on it [pdf]: https://www.jstage.jst.go.jp/article/ddt/14/1/14_2020.01012/... Not many details, just that it worked better than some HIV antivirals. Still, worth ramping up
167.
by comicjk 7y ago
Proposed, yes, but you can't buy it yet. Also, the cheaper tests so far are all antibody tests, not the more accurate RNA tests that everyone is clamoring for. Antibody tests don't work until you have had the infection for a while
168.
by comicjk 7y ago
There is an asymmetric risk, though. Due to feedback loops like methane release, we don't know at what temperature the warming will stop, or how fast it will go. The upper-range estimates are well beyond any temperature from the last 1
169.
by comicjk 7y ago
If funding for these projects is the problem, our society is even more short-sighted than I thought. We should be throwing money at them. I would be more worried about underlying physical constraints, like a shortage of manufacturing throug
170.
by comicjk 7y ago
I work in computational drug discovery. With current hardware, we are basically limited to simulating single proteins for microseconds of time, and even that requires a lot of simplifying assumptions. So we can only simulate a small part of
171.
by comicjk 7y ago
If these first trials succeed, yes, we might get a vaccine mass-produced fast. But you're not looking at the downside risk: if these trials fail, and the next trials fail. This is research; by definition we don't know what will ha
172.
by comicjk 7y ago
This is an underestimate - I'm reading your comment from a 170-year-old wooden house.
173.
by comicjk 7y ago
I like this better than my solution. The technique of adding random numbers has a more crypto feel to it. It would help to use big numbers, so that they would conceal the underlying number better (clearly single-digit numbers would be no he
174.
by comicjk 7y ago
It seems like a plain anonymization problem, much like a voting with a secret ballot. If I encountered this problem in real life, I would just use slips of paper and a box with a slit in it. Possible strengthening techniques would involve r
175.
by comicjk 7y ago
The average company a few years from now will probably be as profitable as the average company last year. But that's survivorship bias: some of the companies from last year might not be around anymore, and it's hard to predict whi
176.
by comicjk 7y ago
The market reacts to expected news, not just current news. The fact that bad news is coming might already be priced in. It's hard to say how bad a piece of news would have to be to make expectations worse.
177.
by comicjk 7y ago
That doesn't follow. If people expected the markets to be back up in two years, they wouldn't be this low right now. Just because the pandemic ends doesn't mean the value of companies returns - some will have shrunk, some wil
178.
by comicjk 7y ago
Important to note that the datasets used are sparse, and that the key to this algorithm is better exploitation of sparsity. The GPU over CPU advantage is a lot lower if you need sparse operations, even with conventional algorithms. "It
179.
by comicjk 7y ago
I think you're comparing bicycles to an idealized version of horses. Real horses get tired quickly, get hurt easily, and are quite expensive. Assuming decent roads, a bicycle would often be more convenient, and almost always cheaper. F
180.
by comicjk 7y ago
"Big" is relative. If a company starts falling apart as soon as the founder can't personally manage everyone, it has a disease of bigness, even though it's still small on some absolute scale.

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