cjbgkagh

26 ms·

661.
by cjbgkagh 1y ago
>> Your approach assumes that the distribution of those SNPs at the population level is immaterial. No it doesn't. >> What makes an allele attractive at one frequency can expose new liabilities at a different frequency
662.
by cjbgkagh 1y ago
In a similar analog to machine learning there are fundamentalists approaches and there are empiricists approaches. Most medical researchers need to be able to defend their work and it’s easier to defend fundamentalist ideas - but they spend
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by cjbgkagh 1y ago
I like the accidental eugenics the USSR did by concentrating their scientists in Akademgorodok (Siberia), the kids born there are unusually smart. Similarly in the USA the SATs for collage admissions did end up with more pairings of smart
664.
by cjbgkagh 1y ago
It would be a matter of concentrating specific SNPs that are already identifiable in human populations. There is no need to create new SNPs of unknown outcomes. There would be no difference if the SNP was put there through intervention or i
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by cjbgkagh 1y ago
It can be both genetic and epigenetic, but concur I was one of those people who believed I was smarter simply because I wanted it more and worked harder. I found out later in life that my outcomes were largely genetic and this has increased
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by cjbgkagh 1y ago
Think of how complex LLMs are and yet their emergent behavior is based on a few very simple rules and an easy to understand loss function. Due to the emergent behavior things can have the appearance of being far more complicated than they a
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by cjbgkagh 1y ago
It's one of those arms race things, and people are already doing this but quietly for obvious reasons. Similar to putting weapons on drones, it used to be unthinkable and now it's unthinkable not to.
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by cjbgkagh 1y ago
I think you're defining harm based on sentience where as my definition of harm would include damage to not sentient objects.
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by cjbgkagh 1y ago
Humanity is getting better at combating pathogens to the point we wouldn't have to rely on genetic diversity for resilience, additionally such treatments could be given to those already born. It's not like human variability would
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by cjbgkagh 1y ago
I should add, what I was told is that they were amazing, especially the pre-IBM Rational stuff. Rational was acquired by IBM in 2003. I was working on tech adjacent to the JSF (F35). I was told by a guy working on the JSF that the extra bug
671.
by cjbgkagh 1y ago
I think IBM Rational Ada was a thing back then. Never used it but heard stories about it.
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by cjbgkagh 1y ago
I’ve been hearing it’s eminent because China is not a democracy, I hear the western perspective. I see revolutions as an alternate elite agitating for change. In my model an effective suppression of an alternative elite is sufficient to pre
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by cjbgkagh 1y ago
I'm pretty sure he gives those as examples of 'restorations' as exceptions to the general trend of society trending left.
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by cjbgkagh 1y ago
> China faces civil unrest and balkanizes, due to backlash against its increasingly authoritarian regime? I've been hearing this is eminent for my entire life.... > major population shock that radically and painfully transforms t
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by cjbgkagh 1y ago
But degrading an other is ok? From the very beginning tech was about making jobs easier, and now it’s easier to make jobs easier, including our own. So I think it’s ethically consistent to be happy about both, even if our own jobs are at ri
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by cjbgkagh 1y ago
While I can admire the effectiveness I do have grave concerns when it’s so cheap to damage very valuable things from such a long distance. Nothing is as safe as it once was and never will be again. The once unthinkable becomes routine, perh
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by cjbgkagh 1y ago
It was at least an economic blockade. I had to double check, I did think they took a more active role, there was a prevention of transit through Panama Canal, and a few other things. If there ever was a time for an economic blockade to be e
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by cjbgkagh 1y ago
Depends if you consider blockades to be an act of war.
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by cjbgkagh 1y ago
Not a lawyer but I think this could result in a duty of care under tort law if people start to reasonably rely on this information to make decisions. If it can be perceived as semi official information then it’s reasonable to expect people
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by cjbgkagh 1y ago
Or just have two calculators and swap them
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by cjbgkagh 1y ago
Ah, you are correct, for some reason only the later mentioned previously approved drug was retained in memory.
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by cjbgkagh 1y ago
Interesting, I have my own hacked together caches to greatly speed up docker setup, having a cache at this level may speed things up further in a cleaner more maintainable way.
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by cjbgkagh 1y ago
It is Tirzepatide which is a GLP-1 agonist, like Semaglutide (Ozempic). I don't know how much of the co-occurring issues from sleep apnea are caused by the sleep apnea or are comorbidities for something else. I suspect quite a lot of t
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by cjbgkagh 1y ago
Ah that seems to explain it to me, if instead of presenting it as breaking some physics they should have said what actually makes it useful. My understanding of it now is that since it can work at a higher temperature in an environment wher
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by cjbgkagh 1y ago
Perhaps someone with a better memory can correct me, but wasn’t ios7 the first iPhone interface where Jony Ive had free range and it was really bad?
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by cjbgkagh 1y ago
They say on https://rive.app/pricing that the Format is OS and MIT, perhaps I have missed something?
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by cjbgkagh 1y ago
I had never head of Rive before and it looks like something I can use in one of my projects. Thanks, this is the kind of stuff that keeps me addicted to HN.
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by cjbgkagh 1y ago
Sorry by designers I mean UI assets. Art and iconography. I recently needed a transpiler for a mini-DSL to Lua. Google Gemini did a pretty good job of it, hallucinated a bunch of non existent helper functions but they were easy enough to ad
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by cjbgkagh 1y ago
I need code that works within the specialized context of my project, I couldn't steal code from GitHub even if I wanted to.
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by cjbgkagh 1y ago
Perception precedes reality, being a dev was already a low status job. Consider a top tier FAANG vs white shoe lawyer. With AI that has dropped further. Even if AI only takes the very junior roles there will be increased competition at the

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