chrisamiller

15 ms·

91.
by chrisamiller 11y ago
Thanks. Guess I should have specified "preferably free" too :)
92.
by chrisamiller 11y ago
Oh man, I use 3 or 4 pipes to filter various RSS feeds. Ugh. Good suggestions for replacements (especially those that don't require my own server) would be much appreciated.
93.
by chrisamiller 11y ago
Well, not quite 50/50... :) https://en.wikipedia.org/wiki/Klinefelter_syndrome
94.
by chrisamiller 11y ago
Yeah, rates are important, but also small sample size (and who's at fault matters - the companies claim that human drivers caused all 4). So you're not wrong, but my point is that humans are awful drivers, prone to distraction and
95.
by chrisamiller 11y ago
In the last 8 months: - Number of human-driving auto accidents in US: ~10.6 mil - Number of self-driving auto accidents in US: 4 Guess which one merited an article? --- Editing to add that all 4 crashes were apparently caused by human drive
96.
by chrisamiller 11y ago
Yeah, that's the primary use, but there has been speculation here and elsewhere that a battery could be worthwhile just for exploiting the difference between peak and off-peak rates. This indicates that, at least for my area and usage,
97.
by chrisamiller 11y ago
A quick analysis of our local (St Louis) rates for an average (1700 sq ft) suburban house indicate that time shifting to get peak rate savings isn't worth it: Payback time on the 10kWh battery would be around 26 years, and on the 7kWh
98.
by chrisamiller 12y ago
I'm with you there. I had a lot more free time in grad school than I do now (both personally and professionally). Judging from the updates I see on twitter and blogs, most of that core group has gone on to bigger, better, more time-con
99.
by chrisamiller 12y ago
I miss that interface and community. Even if FriendFeed was still around, though, I wonder if it would be as popular. That group contained the early adopters of internet communication among scientists, a movement that has now grown exponent
100.
by chrisamiller 12y ago
> I'd be willing to bet that there is a healthy species of bacteria that has stopped evolving, that perfectly copies its dna when it divides, and never transfers dna horizontally There are several flaws in your argument: 1) There is
101.
by chrisamiller 12y ago
Sigh. This gets posted every few months and the title is still wrong. It's a great time to be a scientist, especially if you're into, say, computational biology. It's an awful time to shoot for a tenure track faculty position
102.
by chrisamiller 12y ago
Do you have evidence? If so, I'd like to see those data.
103.
by chrisamiller 12y ago
The field is slowly coming around. I've been very harsh when peer-reviewing papers without proper code release and documentation. I know that I'm not alone. Both investigators and funding agencies are starting to understand the me
104.
by chrisamiller 12y ago
I was worried about commute times from three different points when looking for a house, so I wrote a quick and dirty little ruby script to hit the Google Driving Directions API. It tiles across the area you specify and spits out a kml file
105.
by chrisamiller 12y ago
To be clear, not HN itself, but the community in general is very much about monetizing their work, getting venture capital, making a quick buck, yadda yadda.
106.
by chrisamiller 12y ago
The vast majority of Metafilter pageviews are people who lurk and just read the content. (The $5 barrier to entry and reasonably small community is a feature, not a bug) The vast majority of these lurkers originally hit the ask.metafilter s
107.
by chrisamiller 12y ago
When I'm on metafilter and I click on the 'lawschool' tag, it absolutely makes sense that the header says "Posts tagged with lawschool" Their goal is not to optimize for Google, it's to optimize for users on th
108.
by chrisamiller 13y ago
Simple and useful - thanks!
109.
by chrisamiller 13y ago
FWIW, doesn't seem to allow me to look at the tag 'r'. While I won't argue that R is an awful name for a programming language, it's a legitimate tag: https://stackoverflow.com/questions/tagged&#
110.
by chrisamiller 13y ago
There are some cancers driven by things like mismatch-repair defects, so that the amount of DNA damage grows very quickly over time, but these don't cause the majority of cancers. In liquid (blood) tumors, especially, these are very r
111.
by chrisamiller 13y ago
As a cancer biologist, I can tell you that at least some of these assumptions don't hold true. Acute Myeloid Leukemia is driven entirely by "accumulated lightning bolts". Every time your blood stem cells divide, a small numb
112.
by chrisamiller 13y ago
Even if you've never taken antibiotics, you're in the same boat as everyone else. The resistant bacteria are in the environment. If your immune system works fine, there's less to worry about. The most urgent danger is to the
113.
by chrisamiller 13y ago
Seems overly complex - just paint your roof white and reflect most of that light and heat back into the void of space.
114.
by chrisamiller 14y ago
Tell that to the tens of thousands of researchers who make use of the human reference genome daily. I don't even know what the guy is talking about there - imagining modern genetics or genomics without it is pretty much impossible.
115.
by chrisamiller 14y ago
As someone in the field, let me assure you: This article does not accurately reflect the state of the field.
116.
by chrisamiller 14y ago
Some thoughts on this article: - This guy clearly has a limited understanding of the field. This quote is laughable: "There are only two computationally difficult problems in bioinformatics, sequence alignment and phylogenetic tree construc
117.
by chrisamiller 14y ago
They're already overused in genome biology. They do a beautiful job of representing interchromosomal rearrangements in cancer, but don't actually convey a whole lot of information.
118.
by chrisamiller 14y ago
And there's always the chance that a drug to cure that particular mutation doesn't exist. What then? Spend millions on years of research to make the drug? This is indeed the case for most mutations that we're finding in cancer genomes. (
119.
by chrisamiller 14y ago
To the best of my knowledge, this hasn't been published.
120.
by chrisamiller 14y ago
Most of 23andMe's customers don't really get sequencing. They get genotyped on a SNP chip, which only tells you about a million or so positions (out of ~3.2 billion). The other product that 23andMe is starting to offer is exome sequencing,

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