carlsborg

6 ms·

31.
by carlsborg 1y ago
They released a paper. Preprint linked in page.
32.
by carlsborg 1y ago
Both are broad spectrum antivirals, but completely different mechanism. DRACO "is a chimeric protein with one domain that binds to viral double stranded RNA (dsRNA) and a second domain that induces apoptosis when two or more DRACOs cro
33.
by carlsborg 1y ago
Paper appears to be paywalled. It is however an update to this preprint which is available on Biorxiv: "Broad-spectrum RNA antiviral inspired by ISG15-/- deficiency" https://www.biorxiv.org/content/10.110
34.
by carlsborg 1y ago
Maybe we can crowd source data. My platform, currently in beta, has ai assistants for compute infrastructure and biology and will soon let people to do self serve research on their own omics data using models like yours. So there could be a
35.
by carlsborg 1y ago
Cool. Could we train a "potential oncoprotein" classifier on Orthrus embeddings? IMO self serve diagnosis and detection is a far larger market than synthesis.
36.
by carlsborg 1y ago
Opus is already severely crippled: asking it "whats your usage policy for biology" triggers a usage violation.
37.
by carlsborg 1y ago
> "Earth has 4550 satellites in orbit" Rapidly obsoleted information. SpaceX alone has > 7500 satellites in orbit. It added 2,300+ satellites in the one year period ending Jun 2025.
38.
by carlsborg 1y ago
Also not to be confused with: * Threonine: One of the 20 base amino acids, forms proteins. You need to get it from a food source.
39.
by carlsborg 1y ago
I thought people were dosing themselves with a base amino acid. Duh. Theanine is an amino acid found in green tea, but not a base amino acid, ie doesn't form proteins. Can cross the blood-brain barrier and can certainly modulate brain
40.
Theanine boosts object recognition memory (in rats)(biorxiv.org)
2 points by carlsborg 1y ago|2 comments
41.
by carlsborg 1y ago
The great filter: light years of travel needed by detection probes.
42.
by carlsborg 1y ago
This is critical, more people need to read this.
43.
by carlsborg 2y ago
"Upstream Wayland basically fixed most of the technical things I complained about." in update linked right on top.
44.
by carlsborg 2y ago
Anthropic blog has a nice distinction between LLM Workflows and Agents: LLM Workflows: predefined code paths. Includes retrieval/tools/memory, routing based chatbots, orchestrator-worker, iterative evaluator etc Agents: dynamicall
45.
by carlsborg 2y ago
From a biology perspective base amino acids (such as theanine) on their own are not generally major modulators of human function. You want to experiment with small molecules, something that binds with proteins such as enzymes which in turn
46.
Parachute use when jumping from aircraft: randomized controlled trial [pdf](bmj.com)
1 points by carlsborg 2y ago|1 comments
47.
by carlsborg 2y ago
The official docs reference those numbers.
48.
by carlsborg 2y ago
Its merged into CPython 3.13 but labeled as experimental. Single threaded cpu bound workloads suffer in benchmarks (vs i/o workloads) till they put back the specializing adaptive interpreter (PEP 659) in 3.14. Docs say a 40% hit now, t
49.
Happy Eyeballs IETF Algorithm(en.wikipedia.org)
2 points by carlsborg 2y ago|0 comments
50.
by carlsborg 2y ago
Impressive.
51.
Rise of the RNA machines – self-amplification in mRNA vaccine design(cell.com)
2 points by carlsborg 2y ago|0 comments
52.
by carlsborg 2y ago
The main lichess engine (lila, open source) is a single monolith program that's deployed on a single server. It serves ~5 million games per day. But there are a several other pieces too. They discuss the architecture here https:/
53.
Diffusion models are real time game engines(huggingface.co)
1 points by carlsborg 2y ago|0 comments
54.
by carlsborg 2y ago
Did you look at CDK8s?
55.
by carlsborg 2y ago
Would make sense. Good fit.
56.
A highly efficient sorting-based distributed memory k-mer counter(arxiv.org)
1 points by carlsborg 2y ago|0 comments
57.
CPU-Free Computing: A Vision with a Blueprint (Hot OS XIX) [pdf](sigops.org)
1 points by carlsborg 2y ago|0 comments
58.
by carlsborg 2y ago
Back in 2015, AMD was trading at $2.40 and Nvidia at about 50 cents (accounting for stock splits). 1000 USD invested then would be ~$70,000 and ~$256,000 respectively today.
59.
by carlsborg 2y ago
Admirable level of honesty. Great signalling for culture.
60.
by carlsborg 2y ago
If you ask ChatGPT to reply in the style of Arthur Whitney, you get amazingly concise summaries. Like a language verion of this code. I use that prompt often.

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