blueblimp

12 ms·

1. 151.▲
   by blueblimp 9y ago

   I'm with you on single base edits being mostly not applicable to humans clinically, but... "our ability to make directed changes far outpaces our knowledge of what changes to make" On this point I couldn't disagree more.
2. 152.▲
   by blueblimp 9y ago

   The best minesweeper implementation is Simon Tatham's, because it guarantees a board that can be solved without guessing. http://www.chiark.greenend.org.uk/~sgtatham/puzzles/js/mines... That guarantee al
3. 153.▲
   by blueblimp 10y ago

   Yes: http://www.sciencemag.org/news/2014/09/human-speech-gene-can... . (That said, you'd need to use a different approach in humans, because we don't have any smarter species that we can copy genes f
4. 154.▲
   by blueblimp 10y ago

   It's untested in the sense that no genetic engineering has been done in humans, yes. (Unless you count gene therapy to cure disease, which is fairly different.) However, there are some pretty strong reasons to think it would work, at l
5. 155.▲
   by blueblimp 10y ago

   As others have pointed out, this is a special case of a commutator. I don't know if this case has a standard name, but elsewhere I've seen it called "U-process": https://www.quora.com/Can-a-Rubiks-cube-be