arkades

101 ms·

901.
by arkades 9y ago
>Data The most recent public data from the american association of poison control centers is 2016. For toxicity events alone they don't break out analgesics into sub-groups, but for fatalities acetaminophen is in fifth place with 5.
902.
by arkades 9y ago
> "the fact that clinical trials seek people maximally healthy but for the target conditions rather than a representative sample of those with the target condition is a very frequent complaint." Those aren't quite in contr
903.
by arkades 9y ago
> It seems like the key to making medical progress is realizing that not all treatments are "one size fits all" The medical community has realized this, and been tackling this problem for a few millennia. Hippocrates addressed
904.
by arkades 9y ago
> aspirin wouldn’t pass We have a number of drugs in the same class that are as or more effective with less frequent adverse effects, and the same price to market. It is also one of the leading causes of toxic ODs presenting to the ED. A
905.
by arkades 9y ago
That’s funny. As a doctor with a long background in managed care and healthcare policy, I find the healthcare-related comments here painful to read and extremely painted over with know-it—all-ism. I’ve begun actively avoiding them because o
906.
by arkades 9y ago
They didn’t wait until the final few paragraphs to build this up as a gender/race conflict. “In 2018, skateboarding is going through a similar change from the inside out. There’s increasingly less space between what skateboarding actua
907.
by arkades 9y ago
“ Although police-issue bulletproof vests can stop rounds fired from a handgun, they are useless against assault rifles. “After seeing what little kids can get their hands on, I went out and bought hard plates,” designed for use in war zone
908.
by arkades 9y ago
Registered and used it with, apparently, the blessing of the French government for a couple of decades - they were aware of its existence, and worked with him in providing some content, as I understood the article. It's ... nothing at
909.
by arkades 9y ago
> As soon as I get married ... might bring babies Contraception.
910.
by arkades 9y ago
It is? He’s spent the last three years working in tech in a first-world country while waiting for a chance to work in tech in another first-world country, where he’ll have to not-get-deported for two whole years before he can really settle
911.
by arkades 9y ago
Please elaborate, what is regulation E?
912.
by arkades 9y ago
Isn’t it funny how a companies expensive legal team never “unintentionally” benefits the consumer? Somehow, they always “unintentionally” make things ridiculously in favor of their client. So very funny.
913.
by arkades 9y ago
I think the truth lies in the middle somewhere. I knew absolutely nothing about load balancing before reading OPs comment and the blog post, and while you’re correct that I wouldn’t have retained OPs bullet point version as well as Rachel’s
914.
by arkades 9y ago
“Snappy UI”? On the ps4? After the recent consolidation of all the streaming video options onto a single screen, the additional clicks and loading time has basically made me envy my mom’s roku.
915.
by arkades 9y ago
Perhaps I missed something, but this article didn’t say two Pulitzer winners went into PR. It spoke of a photographer who got a non-journalism job, a journalist who found “greener pastures,” and a third journalist who got a job for the Shoa
916.
by arkades 9y ago
The problem with that being that many states have been expanding their definition of “sex offender” in a harsh-on-crime theme that, over the years, has morphed it into something unintuitive. When you tell me someone is a sex offender, I thi
917.
by arkades 9y ago
It is a business decision. The idea that lawyers exist in their own bubble somewhere and just launch legal missiles when they want to is false. Part of business is “protect our ownership rights,” and you’d better believe execs push the butt
918.
by arkades 9y ago
> t is perfectly permissible to not defend a trademark. A lawyer is not obligated, and cannot, make a trademark owner defend it. When I said “defend as required by law,” I meant “defend the IP in the specific manner dictated by our laws,
919.
by arkades 9y ago
Legislators are mostly lawyers, by tradition. They comprise a barely measurable fraction of 1% of lawyers. They do not make laws to create work for lawyers, as is usually implied in these discussions.
920.
by arkades 9y ago
They submitted via 510(k), a loophole abused by many manufacturers these days. They didn’t have to show this device was safe, just that it’s “substantively similar” to an existing device. The bar for evidence is low-to-laughable.
921.
by arkades 9y ago
There are no lawyers in this thread, huh? My wife is a corporate lawyer, so ive seen a little bit of these shenanigans from her perspective. And it pretty much boils down to this: there are certain risks lawyers can take and keep their jobs
922.
by arkades 9y ago
VitD became a fad topic over a decade ago and has been studied endlessly since then. This is a very odd comment thread. Lots of people criticizing our health system for not studying things it actually does study a lot.
923.
by arkades 9y ago
I find public health inspectors also make it more expensive to run a restaurant. Perhaps the solution to their tight margins would be to abolish health inspections.
924.
by arkades 9y ago
Wait, what’s the first?
925.
by arkades 9y ago
My pleasure
926.
by arkades 9y ago
When a clot blocks off blood flow to an area of the brain you expect that area to die and, as a result, lose its function (“clinical deficit”). The blockage is an infarct; the downstream area suffocating is infarcted. When you look at the a
927.
by arkades 9y ago
Or, as in this case, being a doctor who is also a guy with a computer. :)
928.
by arkades 9y ago
What this story leaves out is why we are moving away from thrombolytics - besides them kinda sucking. Once a clot has matured they tend to be useless, which is part of why there’s a solid upper cap on time to administration. You cross a lin
929.
by arkades 9y ago
In fairness, that was the lens the narrative played up. The other side is, “doctor pursues combination of two apparently shitty drugs for decades without anything but armchair hypothesis for support despite massively accumulating evidence t
930.
by arkades 9y ago
The NYS Office of Mental Health appears to have been breached.

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