adenadel

62 ms·

631.
by adenadel 11y ago
I think dang said recently it was something like 8 hours. Beyond that you can resubmit. I've had cases where I've submitted something and it just takes me to the thread where someone else posted it and it automatically gives them
632.
Psychologists' betting market hints at most reliable research findings(nature.com)
1 points by adenadel 11y ago|0 comments
633.
Catalan Regional Parliament Approves Plan for Independence from Spain(npr.org)
10 points by adenadel 11y ago|1 comments
634.
by adenadel 11y ago
My guess would be that a large number of dual citizens obtained their citizenship in the course of their scientific work. It speaks to the training problem we have.
635.
What Do Professional Apple Farmers Think of People Who Pick Apples for Fun?(theatlantic.com)
2 points by adenadel 11y ago|0 comments
636.
by adenadel 11y ago
With particular hardware and software you can. Edico Dragen claims speeds for bcl -> vcf of 20 minutes [1]. With Microsoft Research's snap aligner and 450GB of memory you can get whole genome alignment in ~30 minutes and then varian
637.
by adenadel 11y ago
I don't agree with you. I would argue that Genomics England is doing genomics right with the 100k genomes project and they certainly aren't doing custom analysis. Their pipeline is standard through variant calling and annotation.
638.
by adenadel 11y ago
Depending on the pipeline you use and the compute resources available you could have a full workflow done in anywhere from several hours to a couple days. Illumina BaseSpace is free (for now) and has some example data sets with a bunch of c
639.
by adenadel 11y ago
Sure, all the time. Network and I/O are the biggest blockers for sequence analysis. For any organization that is working with thousands of genomes they probably have their own compute resources. I know of at least one organization who
640.
by adenadel 11y ago
You've got a bit of misinformation in here. He's correct about the raw sequence data for a 30X whole human genome being 100GB of data. The standard practice is to align the sample to the reference, but we store alignments in the B
641.
by adenadel 11y ago
People say this all the time, but with some of the most common applications of high throughput sequencing there are very good canned solutions (using open source software) that you can pay for. DNAnexus, Seven Bridges, and Illumina BaseSpac
642.
CRISPR Gene Editing to Be Tested on People by 2017, Says Editas(technologyreview.com)
1 points by adenadel 11y ago|0 comments
643.
by adenadel 11y ago
I assumed that they meant unique sequence. The oligo pools for microarrays really only need to be synthesized a single time and a single oligo can be present multiple times. Synthesizing 100M bp is really trivial if you amplify any bit of D
644.
by adenadel 11y ago
Hi Barry, how do you guys know that this accounts for 10% of global DNA synthesis production? Some companies synthesize their own DNA with custom instruments and my guess would be that this production is unaccounted for.
645.
Verge Genomics Picks Up $4M Seed(techcrunch.com)
1 points by adenadel 11y ago|0 comments
646.
Human-Like: Facebook Is Using Our Data to Build the 'World's Best' AI Lab(popsci.com)
1 points by adenadel 11y ago|0 comments
647.
Artificial-intelligence institute launches free science search engine(nature.com)
2 points by adenadel 11y ago|0 comments
648.
Marvin Minsky Reflects on a Life in AI [video](technologyreview.com)
56 points by adenadel 11y ago|16 comments
649.
Marvin Minsky Reflects on a Life in AI [video](technologyreview.com)
11 points by adenadel 11y ago|0 comments
650.
by adenadel 11y ago
Ah, gpus are cheating... :) What I meant about i/o is that if you're reading the data off of disc your read/write time is probably longer than 8 minutes. With SSDs you can obviously go faster. One problem with scaling is that
651.
by adenadel 11y ago
Don't worry, I work for a company in the space and fully understand the challenges :) I have a really hard time believing that you can align a 30x genome in 8 minutes because the I/O time is longer than that, and bowtie doesn&#x27
652.
by adenadel 11y ago
Is anyone using your pipeline? There are lots of fully developed commercial pipelines for human WGS (Illumina BaseSpace, DNAnexus, Seven Bridges, etc.) Depending on the hardware you have available bowtie2 might not be the best aligner. What
653.
AI vs. AI. Two chatbots talking to each other [video](youtube.com)
3 points by adenadel 11y ago|0 comments
654.
Martin Shkreli Won't Suffer Because of That $1-A-Pill Competitor. Here's Why(forbes.com)
2 points by adenadel 11y ago|0 comments
655.
by adenadel 11y ago
I agree completely. The nice thing about the exome is that the knowledge is more extensible than the SNP chip. If we discover new variants within the exome you won't need to be genotyped a second time. That logic probably argues more f
656.
by adenadel 11y ago
I agree with you completely, but comparing from a consumer standpoint the exome gives you a lot more information than the SNP chips for a potentially similar consumer price point.
657.
by adenadel 11y ago
Yes, in fact the UK is doing the first real population sequencing project right now http://www.genomicsengland.co.uk/ This all isn't impossible. HLI is also sequencing well over 10000 genomes per year at this point. Th
658.
by adenadel 11y ago
Do you use a different nanopore than α-hemolysin or MspA?
659.
by adenadel 11y ago
100GB per person for the raw data from 30X WGS
660.
by adenadel 11y ago
Almost all sequencing centers will not hold your data much longer than a few months (and won't put it to any use in that time). The storage requirements are just too high for them to put them on tape and archive them long term. Compani

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