aabaker99

11 ms·

61.
by aabaker99 5y ago
I've not heard of Promethease before this discussion. It appears it will collect literature based on Single Nucleotide Polymorphisms (SNPs) in the DNA you send it. Variant callers are a family of algorithms that look at the DNA in your
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by aabaker99 5y ago
Coverage isn't directly relevant to whether a mutation is deleterious or not. Coverage is about getting accurate reads in the face of short-read sequencing. Modern sequencing will chop up DNA into 200-nucleotide-long fragments and then
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by aabaker99 5y ago
It is true that as the author of a research paper it is my decision how to present it. However, if you're too far off the mark, you are just going to be rejected by peer review or they will ask for revisions. The fact is as a PhD stude
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by aabaker99 5y ago
I'm really happy to see this article here. I quit my PhD where I was working on AI partly because of the "mundane day-to-day fraud" that the author and I observed in the field. Once you've read enough papers, you can eas
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by aabaker99 7y ago
Take these results with a grain of salt. There's a large class imbalance in this dataset and ROC curves can be misleading in this case. The test set contains 269 positive examples and 8482 negative examples. From [1]: > Class imbala
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by aabaker99 7y ago
The false positive information is in the ROC curves such as Figure 2.
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by aabaker99 9y ago
Last time I tried Prefix it didn't work or at least wasn't as convenient as I was expecting. I wish I could give more details than that but I can't remember now. I was and still am really excited by software like Prefix, howe
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by aabaker99 9y ago
It's given that Google will give better search results. They track you. I have the opposite experience regarding programming questions though. I thought that part of the initial appeal of DDG was that it handled queries that involved s
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by aabaker99 9y ago
The OP seems concerned about privacy. Apple certainly has a lot of PR activity promoting privacy of their products. But at the same time it seems so many websites, apps, companies, ISPs, etc. are hoping to track their users much more than b
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by aabaker99 9y ago
Docker can distribute the software needed to run the job well, which is definitely part of the issue and something I should use more. However, I also have in mind a pipeline of scripts where one script may be a prerequisite to the other. C
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by aabaker99 9y ago
I agree and I have been working to do this with some of my pipelines as well. One challenge I have been facing is that my compute environment may be quite different than others'. This is mainly the case with respect to distributed comp
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by aabaker99 9y ago
The virus is inactivated HIV. The risks about long-term side effects pertain more to gene editing than the use of a virus as a delivery mechanism.
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by aabaker99 9y ago
"All models are wrong, but some are useful." -George Box
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by aabaker99 9y ago
my favorite shop would actually use the beans that were about to expire for their cold brew specifically for this reason. they could no longer use the beans for espresso but they still made the best cold brew I have had to date.
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by aabaker99 9y ago
I'm pretty uninformed about libffi but can it help with kind of module interoperability? I've used it to get Ruby to call C functions. I would guess that it could be used for other dynamic languages to call compiled functions such
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Why aren't we sending quadcopters to Mars?(space.stackexchange.com)
1 points by aabaker99 10y ago|0 comments
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by aabaker99 10y ago
Enacting laws under the guise of trying to improve women's health with the effect of closing abortion clinics is only surface level "acting within the public framework of our governance". These laws are ruled unconstitutional
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Double Arm Transplant Surgery(statnews.com)
60 points by aabaker99 10y ago|9 comments
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Citizen scientist hunts for kissing bugs(statnews.com)
70 points by aabaker99 10y ago|24 comments
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by aabaker99 10y ago
I was also surprised by the lack of battery indiciator in awesome-wm. But it took <10 lines of Lua to add. It was a pain at first but now I really like how extensible awesome-wm is.
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by aabaker99 10y ago
For those who are also wondering, this is a preprint. [1] Kaiyuan Yang, Matthew Hicks, Qing Dong, Todd Austin, and Dennis Sylvester, “A2: Analog Malicious Hardware”, Proceedings of the IEEE Symposium on Security and Privacy (Oakland), to ap
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by aabaker99 10y ago
Can you explain this a bit more? I've only read both the abstracts but if I understand right your link deals with compiler-level attacks but the OP deals with hardware-level attacks ("fabrication-time attacker").
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by aabaker99 10y ago
can you comment on why you wouldn't use it? I am somewhere in the middle of software engineering and (biological) data science. I have seen some jupyter notebooks as companions to genomics software and I enjoyed those presentations. I
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by aabaker99 11y ago
I had a very similar problem with Ruby and some of our workloads. I ended up utilizing this evented parser [1] to process smaller subsets of the JSON document and then clear them from memory. The result is a memory usage that is at most the
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by aabaker99 11y ago
this reminds me of a recent presentation posted here about OpenBSD's coming support for "pledges" [1]. I suppose the difference here is that pledges use a single kernel but restrict kernel interfaces for each process while th
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by aabaker99 12y ago
I'm not sure what your OS is but I do something documented at [0] to encrypt my Dropbox files. The encfs approach also makes it easy to decrypt all of them for use. I'd even say with a little more fine tuning (running encfs on sta
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by aabaker99 12y ago
I'm in Houston and it's only 250 miles to Dallas and yet, "You are 706.93 miles away from Ebola at Emory University Hospital! Stay safe!"
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by aabaker99 12y ago
You should mention this behavior of uniq (from the man page on my machine): Note: ’uniq’ does not detect repeated lines unless they are adjacent. You may want to sort the input first, or use ‘sort -u’ without ‘uniq’. Your movies.csv file