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a_bonobo
searching PlanetScale…
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31.
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a_bonobo
4mo ago
At my previous work, I was collating somewhat random unconfirmed animal sightings. I also had a separate database of animal occurrence probabilities (species distribution maps). I'm not a statistician but that sounded like a clear job
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a_bonobo
4mo ago
Ah yes, there is a gap between what our regulator wants and what the reality is. I have no qualms that they'll hover out the data if they want to, we know that since Snowden. But I have to comply with the regulator, not with reality.
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a_bonobo
4mo ago
You can use Claude and Copilot via AWS Bedrock, and there are VSCode plugins for that https://dev.to/aws-builders/setting-up-aws-bedrock-with-clau...
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a_bonobo
4mo ago
3. from my opportunity - For many (not all) LLMs, Bedrock gives you control over which country the data stays in. You have no control over that with the Claude API, for example. We do not work in the US and have strong requirements for the
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a_bonobo
5mo ago
There has been a bit of a 'trend' to rewrite common bioinformatics/comp-bio into faster languages (Rust) via LLMs, OP's repo seems to be an early example. Seqera Labs has a bit of a manifesto: https://rewrites
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a_bonobo
5mo ago
I really like this pattern and use it often, this 'not showing my cards'. The second I hint towards the LLM what I prefer it will become sycophantic and invent nonsense why my preferred solution is better. I'm sure there'
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a_bonobo
5mo ago
Some evidence as to why Brown did not originally win the Pulitzer, instead this citation a few years too late: >Brown’s “Perversion of Justice” series won a prestigious George Polk award. The Herald entered the Epstein series for a Pulit
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a_bonobo
10mo ago
I work on a few HPC systems with unusual, kinda custom-rolled architectures. A whole bunch of Python and R packages fail to compile on these systems. There's no publicly accessible documentation for these HPC systems, nor for these cus
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a_bonobo
10mo ago
>* For years, despite functional evidence and scientific hints accumulating, certain AI researchers continued to claim LLMs were stochastic parrots: probabilistic machines that would: 1. NOT have any representation about the meaning of t
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a_bonobo
10mo ago
Yes, same in Australia. Keep receipts and add the cost to the web form. They have simplified it nicely, though: if you work from home you can claim a per-hour deduction so you don't have to do the math of wear-and-tear, electricity, in
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a_bonobo
10mo ago
> to accurately prepopulate tax returns for around 45% of Americans. (Those other countries have much simpler tax codes than we do.) One should note that the cited study quotes the 45% from a 1992 study. These days, with gig economy and
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a_bonobo
10mo ago
If you can, read Robert Caro's The Path To Power (Caro's The Power Broker has been a HN favorite ever since Aaron Swartz recommended it). It's the story of the first ~30 years of Lyndon B Johnson's life. I forget which c
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a_bonobo
11mo ago
Related, I think people have stopped.... reacting on the internet? I've been part of the X/Twitter to Bluesky migration and people often mention how 'quiet' Bluesky is. I think that's not due to algorithmic interven
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a_bonobo
11mo ago
Bioinformatics has biostars :) https://www.biostars.org/ The difference to linkedin is that biostars has 'in-domain experts' only; the postdocs, the staff bioinformaticians, etc. those are not the people who will
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a_bonobo
11mo ago
In my niche, bioinformatics, linkedin has become somewhat of a force ever since many people left Twitter/X during the 'rebranding'? It's quite weird. They're mostly posts announcing new packages etc. but there seems
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a_bonobo
11mo ago
>I find there is usually also some file juggling, parsing, [...] I'd say I'm 50/50 Python/R for exactly this reason: I write Python code on HPC or a server to parse many, many files, then I get some kind of MB-scale
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a_bonobo
11mo ago
Thanks :) I've gone back to just being vigilant, regular parenting; often joining the games myself. I can recommend 99 Nights In the Forest, nice simple survival-style game with very little in-your-face-monetization.
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a_bonobo
11mo ago
I think that's also because Claude Code (and LLMs) is built by engineers who think of their target audience as engineers; they can only think of the world through their own lenses. Kind of how for the longest time, Google used to be be
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a_bonobo
11mo ago
I've implemented the per-day time limit and it's just broken? It's very hard to measure how much time has been spent on the day, their measure is often above the limit I set, and sometimes a low limit will trigger immediately
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a_bonobo
11mo ago
and gives public presentations at gatherings of the far-far-right party https://www.abc.net.au/news/2025-01-26/elon-musk-supports-af...
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a_bonobo
1y ago
I grew up in Germany, and there are more German translations of Lem than there are English translations - some 'first' English translations are very recent (last 10 years? Like Summae Technologicae?). I've always had a hypoth
52.
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a_bonobo
1y ago
I love Stanislaw Lem. Solaris is his most famous and it has many of his core themes; I'd also try Fiasco. I'm also a huge fan of R.A. Lafferty, but his stuff his harder to find, mostly out of print. Peter Watts' Blindsight is
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a_bonobo
1y ago
Nicely written up in this recent Register article: https://www.theregister.com/2025/10/20/aws_outage_amazon_bra... >Amazon brain drain finally sent AWS down the spout
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a_bonobo
1y ago
Somewhat related: There's this older paper from Lex Flagel and others where they transform DNA-based text, stuff we'd normally analyse via text files, into images and then train CNNs on the images. They managed to get the CNNs to
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a_bonobo
1y ago
I'd also recommend reading up on the Vavilov collection in St. Petersburg: an incredible history. https://www.sciencehistory.org/stories/magazine/the-tragedy-...
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a_bonobo
1y ago
I used to work in such a factory in Germany and turn-over was high :) A large pool of uni students doing their summer breaks propped up the place. They could afford to work there for 1-2 months mentally because they knew they'd go back
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a_bonobo
1y ago
This is kind of that 'climate change skeptic' argument that CO2 is only a tiny percentage in the atmosphere, 0.04%, so anything humans have done to that tiny percentage is therefore negligible. But we've had a massive impact
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a_bonobo
1y ago
Oh that's true. If AI is a bubble, and if it implodes, then MS might be the only AI place left standing if it can get its product into all of the non-tech companies in the world.
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a_bonobo
1y ago
I still think there's a potential niche for 365 Copilot in its boringness. At work (not a tech company), there's an ongoing, slow, 365 rollout. The people who participate in the rollout are not technical in any way, but they all l
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a_bonobo
1y ago
Funny enough, I was an academic for close to a decade before I resigned in disgust; and I feel like OP's article could be Work is not Academia. As an academic, all I needed to do is write papers and get grants, metrics that are easy to
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