_yb2s

52 ms·

721.
by _yb2s 2y ago
Surprised about the mac- I still have a maxed out 2010 Macbook Pro - 16gb ram and SATA- and it has aged so well it is still fully usable with most modern software and workflows, and feels fast. I also have a new Apple Silicon Macbook Pro an
722.
by _yb2s 2y ago
I switched my entire home back to incandescent lights, and put dimmer switches on everything to make them as dim, and warm as possible. High quality incandescent bulbs last effectively forever when dimmed. Our bodies do so much better when
723.
by _yb2s 2y ago
I’m a big fan of using older small form factor commercial office grade laser printers. You can basically get them free, especially if they lack wifi and usb, and most of the time they’ll last for years and years of hard use with essentially
724.
by _yb2s 2y ago
Why are there gaming chairs, and why do they look like race car seats? I drive a sports car that can corner at ~1G and the seats have bolsters on the side to keep your body in place when cornering hard- but they also make the seat uncomfort
725.
by _yb2s 2y ago
Probably depends on the climate and use case… early EVs with no thermal management seems to last forever in coastal areas with mild climates, and slow heavy traffic
726.
by _yb2s 2y ago
To be fair, I think most of the TSA agents are not, many are just doing their job and trying to bring some dignity to a tense situation. I travel a lot and have met some very kind TSA agents. But as an organization, they clearly have a cult
727.
by _yb2s 2y ago
Just saw this one- love the guy's eye contact also. He knows how to stand up to fascist jerks. https://preview.redd.it/travel-safe-for-thanksgiving-v0-i3ja...
728.
by _yb2s 2y ago
TSA will punish you for opting out of anything. If you're lucky, the least they will do is hold you up a long time so you have a good chance of missing your flight. I've also had them sexually harass me, and confiscate (e.g. steal
729.
by _yb2s 2y ago
You’re not understanding what I am saying- there is no way to identify which single cell has a mutation until it is already growing a tumor. There is no way to do what you are proposing -using sequencing to detect cancer mutations early bef
730.
by _yb2s 2y ago
The mutations will just be in single cells a few cells- you’d have to be liquified in order to sequence your whole body for cancer mutations. Leukemia would be an exception though, as you could find that from a blood sample.
731.
by _yb2s 2y ago
Salmon have no "genetic memory" - if you release baby salmon from a hatchery that were bred from adults caught elsewhere, they remember where they were released- not where they are genetically from-, and swim back to the area of t
732.
by _yb2s 2y ago
ECC is not easy to explain, and sounds like a tautology rather than an explanation "error correction is done with error correction"- unless you give a full technical explanation of exactly what ECC is doing.
733.
by _yb2s 2y ago
Physicists switch between square, spherical, and cylindrical cows depending on the coordinate system they are working in. However they would be squares with a unitless volume and length of 1. There is no need for rectangular cows, because y
734.
by _yb2s 2y ago
It made sense to me- they made a risk vs benefit decision under high uncertainty, factoring in the massive harm that the ongoing pandemic was already causing. There had already been 12 years of human clinical trials for other mRNA vaccines,
735.
by _yb2s 2y ago
> Redundancy is not error checking Yes, you are right that DNA repair mechanisms are not technically error correction in the sense that the term is used in computer memory and storage, where any isolated error is mathematically guarantee
736.
by _yb2s 2y ago
There's tons and tons of error checking- we have at least 5 different error correction and repair systems in DNA, cell cycle checkpoints, and extreme redundancy and feedback homeostasis at nearly every level. Every individual cell has
737.
by _yb2s 2y ago
If you shut down one freeway in the LA or SF area, every other one grinds to a halt also- including essentially all non-dead-end local roads... you might as well shut them all down at once, but there aren't enough road crews to repave
738.
by _yb2s 2y ago
I'm not sure what the solution is but there is a gross misallocation of housing in California... the suburban family homes with 4 bedrooms and massive yards designed for kids to play outside are almost exclusively occupied by retired c
739.
by _yb2s 2y ago
Keeping roads perfect requires taking them out of commission for repair... which is a disaster on California freeways that have constant traffic. I think CA does a fair job of balancing that with road condition, and I assume they are alread
740.
by _yb2s 2y ago
Thanks! To clarify, I had no knowledge of the actual technology used, and don't mean to indicate that it is crypographically secure or impossible to exploit. Only that people in the online car communities haven't found simple easy
741.
by _yb2s 2y ago
I recommend using biocmanager to install all R packages- it is very good at automatically resolving dependency issues. The built in R stuff just isn’t great… but there are a few extremely good 3rd party systems Ultimately there is no good s
742.
by _yb2s 2y ago
Why would you use headsets to play with friends in person? The whole point is that you can talk directly, usually with the sound completely off on everyone’s computers, and not too loud music playing in the background For one, if you get a
743.
by _yb2s 2y ago
Yeah almost all Euro cars have had strong cryptography immobilizers since the mid to late 90s. It’s pretty shocking how secure those early systems are - to this day car enthusiasts cannot find any weaknesses or bypasses other than flashing
744.
by _yb2s 2y ago
I think that would be exploited by bad actors- they could e.g. figure out what time of day mods are inactive to best circumvent rules, and know when things were removed in order to re-add them immediately.
745.
by _yb2s 2y ago
I think most (but not all) such things actually did work, and were based on real evidence, we just don’t have easy access to that evidence and context anymore. It is quite likely that modern people are just arrogantly dismissing something t
746.
by _yb2s 2y ago
This doesn’t add up to me either. These are incredibly expensive cars that will bring in a lot of money from just selling them. If you rip up the interior, you’re only going to get what it actually costs to put the vehicle back into sellabl
747.
by _yb2s 2y ago
Some people suspect that is still how many of the AI startups operate
748.
by _yb2s 2y ago
The title is wrong, and is not the actual title of the paper. They discovered some new aspects of how regular mitochondria work, not a new kind of mitochondria.
749.
by _yb2s 2y ago
Yes, there are many mitochondrial diseases related to defects in fission and fusion- it seems plausible that something like what you are suggesting is involved.
750.
by _yb2s 2y ago
Slow down there Dr. Strangelove

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