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Thriptic
searching PlanetScale…
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68 ms
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721.
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by
Thriptic
11y ago
The United States already has one of the highest corporate tax rates in the entire world. We also spend more on education per capita than almost any other country. The problem isn't necessarily lack of money. The problem is that our co
722.
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by
Thriptic
11y ago
> Yes, it's your product, but this is my home! My stance is that EULAs are bullshit, period. If you purchase a product, it is yours, and no one should be able to dictate how you use it.
723.
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by
Thriptic
11y ago
I was fat my whole life and I didn't find it hard; I just needed people to show me the method for weight loss (in my case Atkins then IIFYM). Applying the method was fairly straight forward after a week or two of practice and experimen
724.
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by
Thriptic
11y ago
I'm not sure. I personally was overweight as a child and obese at 23. I never really attempted dieting because it was always presented as a complicated process which was rarely successful. Only after someone else experienced success on
725.
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by
Thriptic
11y ago
Possibly a bit. As someone who lost about about 100 lbs and kept the weight off, I've never really understood where this concept of "fat shaming" came from. I look at obesity the same way I look at smoking: - They are both se
726.
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by
Thriptic
11y ago
Absolutely awesome. I am about to embark on a large image processing / ML project for work. This is just what I need!
727.
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by
Thriptic
11y ago
On the surface this arrangement doesn't strike me as being that different from university police departments, which have been in existence successfully for quite some time.
728.
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by
Thriptic
11y ago
A research compound doesn't need to be 100% pure. It's not meant for human use.
729.
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by
Thriptic
11y ago
> Government is often quite efficient. For example, public health insurance has smaller overhead (like five fold less) than equivalent private products. I don't have the numbers so I can't speak to the overhead, but I can point
730.
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by
Thriptic
11y ago
> Total spending on clinical trials is estimated to be about $25 billion. Not chump change, but easily fundable, and ridiculously easy to offset with the cost savings in terms of Medicare. You're assuming that the government is as g
731.
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by
Thriptic
11y ago
> Doesn't every penny of "old people drugs" development come from selling drugs to old people paid solely by medicare? I'm not sure what this statement means. Drug development costs are accrued by the company before t
732.
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by
Thriptic
11y ago
> It already does, to a great extent, and it's so heavily involved in the process it seems natural to make them eat the costs As far as I know, the government has minimal involvement / skin in the private development process as
733.
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by
Thriptic
11y ago
80 million dollars wouldn't even begin to cover the development / trial costs of a single drug, let alone many. Many drugs also fail late in the clinical trial process (phase 2+), meaning that 80 million dollars would just disappe
734.
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by
Thriptic
11y ago
> They create a lot of attention for barbell training where there previously was none. This. As a powerlifter I used to hate everything about crossfit, but now I realize it's a great way to get people away from pseudo body building
735.
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by
Thriptic
11y ago
Can we please have one discussion on hacker news that doesn't devolve into a discussion about inequality
736.
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by
Thriptic
11y ago
> When I see a big, tattoo covered individual I feel more nervous than unmarked, average sized individuals. Having grown up with a sister who eventually majored in photography I know plenty of tattoo'd people who are amazing people
737.
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by
Thriptic
11y ago
They probably sourced it from Sigma Aldrich, although I'm not sure who Sigma uses as a supplier.
738.
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by
Thriptic
11y ago
I can't think of a worse message to send to potential female competitors than "you're only on this team because we needed some women for appearances".
739.
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by
Thriptic
11y ago
> This will continue to happen time and again until we put in place good checks against businesses consolidating too much power. Wouldn't another fix be public financing of campaigns and a ban on contributing private money to electe
740.
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by
Thriptic
11y ago
My pet peeve is when drivers try to tell me that their machine to process credit cards is broken and I need to pay in cash (so that they can avoid a payment processing fee). When I respond that I don't have any cash and that they'
741.
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by
Thriptic
11y ago
If they start refusing trips or jack the price I will take my business to lyft. Competition dissuades companies from engaging in that type of behavior far better than legislation ever would.
742.
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by
Thriptic
11y ago
In addition (adding on to my comment below), companies don't want the FDA to try to use the outcomes of patients taking the drug for compassionate use as a metric of efficacy before a proper phase 2 or 3 clinical trial has been run, fo
743.
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by
Thriptic
11y ago
In very sick patients (those generally filing for compassionate use) it's sometimes difficult to pin down whether the drug actually caused a problem or death. Were the patients properly adherent? Did they have comorbidities? Were they
744.
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by
Thriptic
11y ago
One of the big impediments against more companies engaging in compassionate use is required adverse event reporting to the FDA. To my knowledge (clinicians / clinical research specialists please correct me here if I'm wrong) compa
745.
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by
Thriptic
11y ago
> Hm, the OP asked what would I do to overcome lethargy. I personally would not lift weights, preferring instead the other forms of cardio activity I mentioned... so that is why I answered the OP's question as I did. This comment wa
746.
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by
Thriptic
11y ago
Parent poster thoughtfully edited their comment in response to the comment you are critiquing, which is why that comment comes off as strange and negative; it is out of context.
747.
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by
Thriptic
11y ago
> and there are quite a few things I personally don't like in current US, and would not see many reasons to be proud. As an American, I agree that we don't have much to be proud of lately, but I think that's why it's
748.
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by
Thriptic
11y ago
Great, but that's not how your post reads. Your post comes off as you stating that cardio is inherently better that lifting w.r.t OP's goals. You don't say anywhere that you are presenting an opinion or what happens to work f
749.
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by
Thriptic
11y ago
> Cardiovascular is the best thing. Not weight lifting, but running, swimming, or fast walking, biking, any of those things. What makes you say this? I always feel fantastic and motivated after a hard session in the gym. I agree that lon
750.
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by
Thriptic
11y ago
It really depends on the lifting. Heavy squats, deadlifts etc? Sure. The pseudo-bodybuilding a lot of people do when they hit the gym? Not really.
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