KempyKolibri

8 ms·

91.
by KempyKolibri 1y ago
This would be a fair analogy if we didn't have studies with a temporal component, but we do. We look at individuals before they get disease then track them over time to see what predicts disease. So we can see, per your analogy, that
92.
by KempyKolibri 1y ago
I'm not sure I follow - is this what you're saying: P1: exposure X is not causally linked to outcome Y if some individuals with lower exposure to X have outcome Y. P2: some individuals with lower exposure to serum cholesterol have
93.
by KempyKolibri 1y ago
Why do we see lower mortality in mendelian randomisation studies for individuals with SNPs that code for lower cholesterol, then?
94.
by KempyKolibri 1y ago
This doesn't question the cholesterol hypothesis. The link between higher ApoB and increased risk of CVD and death is one of (if not the ) best understood and well researched exposure/outcome relationships in human health researc
95.
by KempyKolibri 1y ago
This doesn't really seem to pan out in reality. Often people with small dense LDL have it as a result of other risk markers. There's a good discussion here - https://www.youtube.com/watch?v=kplh30RmYo8 - the long
96.
by KempyKolibri 1y ago
“It’s not just x, it’s y” every three sentences. Ugh.
97.
by KempyKolibri 1y ago
I think that depends on context. In some cases (sweet vs salted popcorn) perhaps we could say that, but in others (rotten vs fresh meat) it may well still be subjective (there are people with heterodox taste preferences out there!), but I w
98.
by KempyKolibri 1y ago
In what sense does it “question all knowledge”?
99.
by KempyKolibri 1y ago
Currently yes. There are some really promising drugs in the pipeline that are doing well in trials, though.
100.
by KempyKolibri 1y ago
What’s the practical difference as far as the appeal to nature argument you’re making goes? Humans lived for thousands of years on maggot-riddled meat, same as they did on parasite-riddled salmon. Surely if it was good enough for us to live
101.
by KempyKolibri 1y ago
Still not sure what your contention with the OP is. They said lab meat solves problems inherent to non-lab meat. This seems to be trivially true. It could also be true that consuming 10% of the meat you normally consume would also reduce th
102.
by KempyKolibri 1y ago
Yeah, I'm personally very bullish on processed and ultra-processed food. If we make it that far as a race, I suspect in 100 years from now we'll be eating a more processed diet and it will be more healthful than our current diet
103.
by KempyKolibri 1y ago
I'm not sure I understand this argument. The point is that there are some serious issues with the production of meat that are not (or may not be in future) issues with lab grown meat. It's true that you could solve this by only ea
104.
by KempyKolibri 1y ago
What do you mean by “part of the circle of life”? I’m not sure why that would be a compelling reason to be ok with something either way? For most of human history eating meat riddled with maggots was part of the circle of life, is it weird
105.
by KempyKolibri 1y ago
If one is going to make sweeping generalisations based on cross sectional data, you have to be open to all the sweeping generalisations. So is it also easy to wonder if there’s a connection between high canola consumption and the fact we’
106.
by KempyKolibri 1y ago
Yep, and we can even see it in others. I have little doubt that if the person I replied to was a passenger in a car, the driver got cut off by someone and they responded by making a sweeping generalisation about people of that race/gen
107.
by KempyKolibri 1y ago
Eh, I think there are several reasons to favour the empirics we have on the subject over anecdotal experiences, which are going to be coloured by problematic biases (toupee fallacy, etc). When we look at the data on the subject, both in ter
108.
by KempyKolibri 1y ago
I think the world would be a better place if everyone went vegan. However, I’m not convinced that vegan activism via pointing out that many people’s behaviours are at odds with their stated ethical preferences is particularly effective. I s
109.
by KempyKolibri 1y ago
Depends on the context, not necessarily weird. If the choice was between “world A” where sentient beings were perpetually bred into existence to be perpetually tortured until they died and “world B” where the breeding stopped and the beings
110.
by KempyKolibri 1y ago
I don’t think people eating butter instead of canola oil is what upsets people. It’s people ignoring the mountain of evidence that such a switch would be a backwards step for health outcomes and claiming the opposite because they read a boo
111.
by KempyKolibri 1y ago
The thing is, we don’t even have good evidence that UPF is necessarily harmful. Whey protein is UPF, but is associated with positive outcomes. Mass produced wholemeal bread is UPF, but is associated with good outcomes. I’m not convinced tha
112.
by KempyKolibri 1y ago
The new(ish) Adobe Project Indigo attempts to rectify some of these - it generally captures pictures in a more SLR-ish manner, even when it outputs HDR. It does RAW capture and has decent control options if you want that. However, it's
113.
by KempyKolibri 1y ago
Yeah, same here I’m afraid. Could be a “me” thing, but I was going to download until I saw it was a subscription model.
114.
by KempyKolibri 2y ago
Great piece - FYI there’s a typo in the tagline: “Turning LLMs into coding experts and how to take advantage <of?> them.”
115.
by KempyKolibri 2y ago
Oh my god, I just thought my typing accuracy mysteriously dropped off at the Lock Screen. My password is long enough that it’s not clear whether a new dot has appeared, but I get frequent rejections.
116.
by KempyKolibri 2y ago
The smaller bins approach is adjustment via stratification. Good primer on both here: https://www.mynutritionscience.com/p/statistical-adjustment
117.
by KempyKolibri 2y ago
I think that’s a fair critique! Probably would have been better to say that the intuitive position was that smoking was unrelated to lung cancer.
118.
by KempyKolibri 2y ago
I’ve heard Miguel Hernán’s “What If” is also excellent, but not got round to reading it.
119.
by KempyKolibri 2y ago
Dismissing all observational study designs out of hand because they can be difficult and easy to perform poorly seems like quite the take. I see this all the time in people’s interpretation of nutrition research, and they do exactly as this
120.
by KempyKolibri 2y ago
It’s certainly possible that there are long term side effects from GLP-1 agonists, but we can only go with the data we have. The five year data (which definitely has limitations in terms of the kind of inferences we can draw from it) is su

More ›