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JunkDNA
searching PlanetScale…
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10 ms
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61.
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by
JunkDNA
9y ago
Still waiting for the peer reviewed publication in a prestigious medical journal that demonstrates doctors using Watson get better outcomes for their patients.
62.
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by
JunkDNA
9y ago
I would argue that drowning is likely a pretty important form of selective pressure in the evolution of these animals. Marine mammals that are able to avoid predation and hunt for extended periods without surfacing would outcompete peers w
63.
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Why We Need More Data Sharing in Cancer Care
(linkedin.com)
1 points
by
JunkDNA
9y ago
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0 comments
64.
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by
JunkDNA
9y ago
In a lab that does clinical work, replacing a single instrument could mean having to re-validate all the tests the lab does, update protocols, get inspections from regulatory bodies, etc... it requires people to spend large amounts of time
65.
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by
JunkDNA
10y ago
Pharmaceuticals are a great example. The actual chemical compounds are mostly trivial to manufacture. This is the central reason generic drugs are so cheap. Once you know a particular chemical is useful as a drug and someone else has done t
66.
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by
JunkDNA
10y ago
The field of study that most directly relates to what you describe is Medicinal Chemistry ( https://en.wikipedia.org/wiki/Medicinal_chemistry ) It's a fascinating discipline. Typically for any given drug, large numb
67.
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by
JunkDNA
10y ago
I disagree with your statement "in some cases". It's "most cases" and where it is not, those are the ones that get the attention and screaming headlines. Shrekli is in the news precisely because this behavior is not
68.
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by
JunkDNA
10y ago
Because it's not about how expensive it is to actually make the drug. To use a software analogy, Oracle doesn't price their database software by what it costs in bandwidth for you to come to their site and download the latest vers
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by
JunkDNA
10y ago
Feels great because my 90's self can look into the future of the early 2000's and see what Windows was like when malware first erupted on the scene and ordinary people were totally unprepared to handle it. I am happy to trade my f
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by
JunkDNA
10y ago
See this article from the scientific journal _Science_ from 2001 (not endorsing the linked website, it was just the first non-paywalled location of the article): http://garytaubes.com/wp-content/uploads/2011/0
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The Managerial Entitlement Complex
(m.signalvnoise.com)
1 points
by
JunkDNA
10y ago
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0 comments
72.
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by
JunkDNA
10y ago
Boy this site makes me understand why the wirecutter exists. Just tell me which is the best so I know.
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by
JunkDNA
10y ago
This thread is fascinating to me. I watched the whole movie thinking that they had found an amazingly good Cushing look-alike. I had no clue it was CGI until I came home to read the spoilers. Curious if the people that thought Tarkin looked
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by
JunkDNA
10y ago
I worked in a reasonably sized organization that was heavily invested in MS products. If I had used SQL Server I would have had access to DBA's and secondary apps we were already licensing for ETL, reporting, etc... I chose postgres be
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I thought I was designing for SpaceX, it may have been for the Silk Road
(words.motel.is)
346 points
by
JunkDNA
10y ago
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129 comments
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by
JunkDNA
10y ago
So does this mean Disney will be able to keep making movies with Darth Vader's "real" voice until the heat death of the universe?
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Speed as a Habit
(firstround.com)
2 points
by
JunkDNA
10y ago
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0 comments
78.
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by
JunkDNA
10y ago
Not to go too far off topic, but I'm surprised at the number of vim users in this thread who still use the escape key and haven't mapped it to something that doesn't require you to move your finger to the most inconvenient sp
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by
JunkDNA
10y ago
My uncle still does inventory for his business (small dancewear retailer) on an Apple II. I believe he recently "upgraded" to the IIgs because he started having trouble getting parts.
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by
JunkDNA
10y ago
To all the folks in this thread suggesting 3D printing and all sorts of other ideas, keep in mind that Sanofi is not some fly-by-night or scrappy startup. They are a major pharmaceutical company with decades of experience manufacturing phar
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by
JunkDNA
10y ago
In general antibiotic resistance is lost when it doesn't confer an advantage. In some cases resistance to antibiotics costs cells energy they'd much rather be spending on other things. When the antibiotic is gone, cells without th
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by
JunkDNA
10y ago
You're right about incentives being wrong, but I disagree with the preference for chronic drugs being a primary factor. In my opinion, the primary incentive killer is that agencies like the FDA will not approve a truly new antibiotic f
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by
JunkDNA
11y ago
Didn't the Napster moment happen in the late 1970's when John Bogle started Vanguard?
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by
JunkDNA
11y ago
The Amiga was so far ahead of its time it was truly remarkable. I would have friends over and show them my computer games and they would be stunned. The Amiga was a contemporary platform of the original 8-bit Nintendo and most people had PC
85.
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by
JunkDNA
11y ago
One place where I ran into this was when I was building an ETL framework in Scala. The scenario was that I wanted to be able to move data from one database system to another and not have the end user of the DSL have to care about the types
86.
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by
JunkDNA
11y ago
Syapse Inc -- Palo Alto, CA & Philadelphia, PA Role: Senior Customer Solutions Software Engineer (Python/JavaScript) Be a part of a team helping to cure cancer, stop heart disease, and deliver the right drugs to the right people at
87.
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by
JunkDNA
11y ago
Syapse Inc -- Palo Alto, CA & Philadelphia, PA Roles: Customer Solutions Software Engineer (Python/JavaScript), Customer Solutions Project Manager Be a part of a team helping to cure cancer, stop heart disease, and deliver the righ
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by
JunkDNA
11y ago
"Never" is a pretty log time. Curious what reasons you have for making that statement?
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by
JunkDNA
11y ago
Syapse Inc -- Palo Alto, CA & Philadelphia, PA Roles: Customer Solutions Software Engineer (Python/JavaScript), Customer Solutions Project Manager Be a part of a team helping to cure cancer, stop heart disease, and deliver the righ
90.
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by
JunkDNA
12y ago
Syapse Inc -- Palo Alto & Philadelphia, PA Roles: Customer Solutions Software Engineer (Python/JavaScript), Customer Solutions Project Manager Be a part of a team helping to cure cancer, stop heart disease, and deliver the right dr
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