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JunkDNA
searching PlanetScale…
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33 ms
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301.
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by
JunkDNA
14y ago
I disagree with his point on the Bible remaining in physical form. There are huge advantages to being able to use hyperlinked footnotes to read more of the context of the prose "in-line". In many Catholic study versions, you can find almost
302.
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JunkDNA
14y ago
Have you ever tried scrolling with an e-ink display? Maybe the absolute latest ones are better but using the kindle web browser on my 2 year old kindle is an unpleasant experience.
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by
JunkDNA
14y ago
Thanks for taking the time to comment here. I'm curious of this is such a widespread problem, presumably organizations like the FAA and researchers would have survey data from pilots that demonstrate how widespread the problem is (I would t
304.
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JunkDNA
14y ago
I often comment on "promising" cancer therapies around here when people get too caught up in the hyperbole of press releases. This one however is a huge deal. For those of you following along at home, note that actual people (very, very s
305.
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by
JunkDNA
14y ago
The article mentions a potential application using lenses with incredible properties. Could one use these materials to make a lens that focuses x-rays? It has been postulated for decades that if one could use an x-ray light source for micro
306.
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by
JunkDNA
14y ago
This is a clever idea, but likely to end badly in practice given the way genetics works. Any neutral trait that doesn't confer increased survivability will be filtered out rapidly and never spread. So you would need to design something that
307.
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by
JunkDNA
14y ago
I studied antibiotic resistance when I worked in pharma. It's a fiendishly difficult problem. You have a mix of factors that all conspire to a bad outcome. First, you have natural selection, so any antibiotic safe for human consumption is l
308.
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by
JunkDNA
14y ago
For health records the regulations are a bit of a confusing mess when it comes to cloud storage. Basically, it boils down to "whatever your organization's legal team says". In theory, if data is encrypted in transit, encrypted at rest, and
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by
JunkDNA
14y ago
I have to say, MS Money might be the only product from MS that I genuinely loved . I was a big fan of MS for years, but in the mid-2000's the security stuff on XP got to be too much. After leaving Windows for the Mac in 2005, Money was the
310.
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by
JunkDNA
14y ago
Philadelphia, PA The Children's Hospital of Philadelphia We're not technically a start-up, but our small group inside CHOP is striving to be a startup within a larger organization. See my interview at OSCON for why you might want to work fo
311.
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by
JunkDNA
14y ago
Man to be your age and feel what you're feeling right now! I had grandiose plans as an 11 year old to write games on the Amiga. But without the Internet and relying only on books learning was a slow process. It ultimately never happened. I
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by
JunkDNA
14y ago
Anyone know if this would also work with an older laptop where you replace the optical drive with a HDD and put an SSD in the hard disk bay? That could breathe some life into my aging late 2008 Macbook 13".
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JunkDNA
14y ago
Indeed. Whenever I see an article like this, I immediately start skimming for discussion of variance and confidence intervals. Wihout them, you can't really know what is going on.
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JunkDNA
14y ago
The tilted "S" in most of those is dreadful. It's all I can look at when I look at them. Additionally, many of them require "work" to read (140, 130, 135). Nuber 89 is the only one that is even borderline useful. There is just too much goin
315.
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JunkDNA
14y ago
Home 3D Printer for clothing and textiles. Textile knitting machines have been digital for close to 100 years (old ones used chains with risers that would change the gears of the machines to change the knit). For simple garments, there's a
316.
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JunkDNA
14y ago
I guess I tend to think about it like this: is the current state of the art for programming the best that we can ever do? If the answer is "no" (which it most certainly is), then what does the future look like? Great strides have been made
317.
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JunkDNA
14y ago
If you are a skeptic on this, I really urge you to listen to Bret Victor. I have generally been skeptical of these kinds of things in the past, but just in the last week Bret Victor's talk ( http://youtu.be/PUv66718DII ) combined with his e
318.
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JunkDNA
14y ago
It's about what people choose to know. There are many people who don't want to know about things they can't always do something about. Many people would rather live a carefree life than know they can get a particular disease. This is a poin
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JunkDNA
14y ago
At most institutions, there already is such a system in place. Research subjects are typically anonymous to the research team, but there's a 3rd party "honest broker" who maintains the link. It's not a technical problem as much as a polic
320.
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by
JunkDNA
14y ago
>Some people may be creeped out by a fully sequenced genetic code Just to be clear to others reading this. 23andMe SNP results are a far cry from being "fully sequenced". The technology to do full sequencing is out there, and it's way,
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JunkDNA
14y ago
You're getting at the heart of the matter as far as the complexity, but just to put an even finer point on the it: A single gene sequence can code for many different alternate versions of the same protein. These different variations can hav
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JunkDNA
14y ago
Well there's a couple of things at work. For one, the key barrier to "clinical demand" is that clinicians (other than highly specialized ones) are not really prepared for dealing with genetic results. Most primary care doctors haven't thoug
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JunkDNA
14y ago
I'm on one of the NIH grants to look at the impact of clinical genomic sequencing on patients, which includes a bioethics perspective. The hardest thing is definitely that our ability to measure greatly outpaces our ability provide meaningf
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JunkDNA
14y ago
This made me pause and think about what might be needed when I get old. Will the nursing home need to have a vintage Macbook seeded with data from The Internet Archive so I can obsessively check Hacker News and Twitter to see if anything is
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JunkDNA
14y ago
Yes, the microfluidics used today make use of this for reading large numbers of small segments of DNA in parallel. The current "gold standard" for DNA sequencing (manufactured by Illumina) uses millions of tiny fragments of DNA which are re
326.
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JunkDNA
14y ago
While it's true you'd get XML from NIH, as a first pass, just extracting the MEDLINE titles and abstracts into plaintext and then running this over them would be enough. You need to complete a license agreement (annoyingly) to download them
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JunkDNA
14y ago
Would love to see what clusters from PubMed would look like. Anyone planning to run this on it?
328.
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JunkDNA
14y ago
>Theoretically no one should have to crawl the web. The information should be organised when it is entered into the index. What do you mean by this statement? I can see from your post you have a contrarian view on how to organize and fi
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JunkDNA
14y ago
Question: You've just won a trip to some interesting far off place (Australia, Italy, Peru, Alaska… whatever). Do you go out the day before you leave, and buy the latest $2,000 DSLR so you can get the best possible photos? Practically anyon
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Embedded Image Data Processing on Mars (from "Beautiful Data") [pdf]
(cdn.oreilly.com)
2 points
by
JunkDNA
14y ago
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