Y
HN Search
Hacker News Search
new
|
comments
|
top
|
jobs
ImaCake
searching PlanetScale…
1.
▲
2.
▲
3.
▲
4.
▲
5.
▲
6.
▲
60 ms
·
721.
▲
by
ImaCake
6y ago
>Maybe I'm privileged to have had this option You are privileged, and I definitely am too. But a simple, extreme, counterfactual works to demonstrate that many do not get this option: Picture a working mother with three children to
722.
▲
by
ImaCake
6y ago
Yep. If the UK is anything like Australia, they will have a small army of contractors who specialise in building SQL databases for various important and pointless requirements for the government. These contractors are used to working on gia
723.
▲
by
ImaCake
6y ago
I mean, statistics relies heavily on calculus. It might be best to try and fit both in. Something at least a little bit fun and educational could be achieved with some dice throwing or simple computer simulations. High school students place
724.
▲
by
ImaCake
6y ago
Mostly just making sure I looked like I was doing something whenever I knew I was within view of the lab manager. I also avoided my desk between tasks since it was close to said manager. Although I did useful things when at my desk I got
725.
▲
by
ImaCake
6y ago
Especially when everyone else got fired at the same time and finds themselves in a game of musical chairs for the few remaining jobs. You don't care if it means oppressive surveillance, at least you can pay your mortage and send your k
726.
▲
by
ImaCake
6y ago
I work as a research assistant in a wetlab (i.e. I physically do experiments). In a previous job the lab manager was suspicious of me appearing to not be doing any work sometimes. Once I figured out I was being watched I went to extra effor
727.
▲
by
ImaCake
6y ago
I particularly like the closing comments about how we teach math. It is something of a theme that we do a bad job of explaining why math should be taught. It took me many years in academic research to realise that not only was math useful t
728.
▲
by
ImaCake
6y ago
What advice have you implemented based on the book? I haven't read it but would love to hear what people have done based on it. I often think about this kind of thing when waiting in line or looking for a carpark. But I have never read
729.
▲
by
ImaCake
6y ago
Yep I think you are right. It does seem to be when VScode tries to auto activate it. This github issue had a solution in the form of adding an empty string for a particular option in settings.json [0]. This fixed it for my mac install. I ca
730.
▲
by
ImaCake
6y ago
>I have converted to VSCode because it just works and I don't have to mess with PATH or whatever. While I love VSCode and use it every day (mostly for markdown), I have definitely needed to play around with PATHs to get VSCode worki
731.
▲
by
ImaCake
6y ago
Just to provide anecdata against the current comments. I totally agree with you. It's not particularly hard if you are pretty tech savvy, but the for the average user you pretty much are stuck with adobe. Or you can try your luck with
732.
▲
by
ImaCake
6y ago
I actually went back into academia to try and maximise my utility. I am not particularly interested in forging my own path in enterprise or as the head of a laboratory. Instead I try to be a helper within other people's teams. This see
733.
▲
by
ImaCake
6y ago
>10 Arguments for deleting your social media I thoroughly enjoyed this book. Mostly for this golden quote which I have saved: >Cats have done the seemingly impossible: They’ve integrated themselves into the modern high-tech world with
734.
▲
by
ImaCake
6y ago
Sometimes I have commented on facebook forgetting it was not HN or another niche community. If you start talking about how your country's weather bureau monitors itself for forecast accuracy then you will almost certainly be met with s
735.
▲
by
ImaCake
6y ago
A solution that seems to work for me is keep notes instead. If I am interested in something I stick a link and some brief notes in a markdown document and make sure to include as many descriptive words as possible. That way I can grep my no
736.
▲
by
ImaCake
6y ago
This sounds an awful lot like research at a university. It definitely has it's strenths and weaknesses. Some labs collaborate more than others. Some feel like islands in the ocean, while others feel like a townhouse in the city. Some l
737.
▲
by
ImaCake
6y ago
For those interested, one can get from a uniform distribution to pretty much any defined statistical distribution using just the uniform random number generator and the inverse cumulative distribution function of the desired random distribu
738.
▲
by
ImaCake
6y ago
That is a fantastic resource. It never occured to me that such a thing would exist, but now that I know it does, I find it hard to think of how it wouldn't - since so much of the internet would rely on these kind of tricks to keep work
739.
▲
by
ImaCake
6y ago
>Why is that the case? And are there any promising theories for how we might overcome that problem? I am still quite new to CRISPR so I am unsure what people are doing to solve this problem. As for why, I would say that the problem is th
740.
▲
by
ImaCake
6y ago
Since you are curious I will try to answer with a bit of a tangent :) But, in short, the real problem is the unintended edits that happen at the same time. Because if you mutate a bunch of stuff in a cell, you will probably end up giving
741.
▲
by
ImaCake
6y ago
This is a good point, it can be hard to predict what gene does what. Most genes that have been targetted for gene therapies tend to be the singular and known source of a genetic disease. Something like the sodium transporter mutation in cys
742.
▲
by
ImaCake
6y ago
Yes, plenty of examples of gene editing in sick adult humans in the literature :) We have done the same with older techniques using zinc finger nucleases (same mechanism, but much more difficult to "program) and also infecting cells wi
743.
▲
by
ImaCake
6y ago
Maybe management keeps saying this to scare the operations people into working harder. Lots of arsehole managers think this is the way to hold onto staff and make them work harder. Of course it really doesn't work that way, but maybe s
744.
▲
by
ImaCake
6y ago
Unless I am unaware of something, CRISPR is not yet ready for medical usage. Sure, it is an amazing research tool. But every gene editing trick built on the back of this incredibly useful protein (Cas9, that is) has "off-target" e
745.
▲
by
ImaCake
6y ago
I don't think I have a motto, and I don't particularly want a single one. Instead I rely on a broad set of ideas and rules which guide my decisions. Here is one quote that guides my thinking about science and philosophy: “Nell d
746.
▲
by
ImaCake
6y ago
That's the joke! The quote is meant to be absurd. I've seen this quote generate some interesting discussion before. People seem divided into two camps over whether to take it seriously or as absurdist humour.
747.
▲
by
ImaCake
6y ago
This is why I use my quotes and note collection as a set of reminders and stories. The result is that my collected notes have each become longer over time; early quotes are one or two sentences, now I rarely save anything less than half a p
748.
▲
by
ImaCake
6y ago
This is fascinating. Glad it has an RSS feed so I can come back for more later.
749.
▲
by
ImaCake
6y ago
That is a failure of hotel quarantine. The lockdown that followed was harsh and it worked. I am in another Australian state, the lockdowns have been lifted and I can go to work with little fear of contracting COVID.
750.
▲
by
ImaCake
6y ago
Turns out science opinion changes with new evidence. When this all started the evidence did not suggest masks would help. Turns out they do, so now the science advice has changed. So your argument is because science is working as intend we
More ›