ImaCake

24 ms·

421.
by ImaCake 5y ago
> You cannot say this for certain There are dozens of countries that held off the pandemic for over a year. They mostly had the advantage of being islands. > Claiming these lockdowns and restrictions didn't have a significant imp
422.
by ImaCake 5y ago
Yes, I have some training in adjacent areas and have found the political argument very frustrating. The molecular evidence is very compelling for natural evolution. The idea of a naturally discovered virus leaking from a lab is plausible, b
423.
by ImaCake 5y ago
The uploading process is done using code. It is super easy to screw it up especially if you are a trained biologist who learnt some python and bash from some random websites that stole their content from stackoverflow. So the process is the
424.
by ImaCake 5y ago
A lot of people would, and did, isolate even without being told too until they were vaccinated. They would have done so out of fear. All that governments really did by mandating lockdowns was enforce it on the part of the population that wo
425.
by ImaCake 5y ago
Woops yes. If you sum them together you do get a normal dist. Come to think of it a cumulative normal distribution is a sigmoid.
426.
by ImaCake 5y ago
I’m no expert, just a humble biostatistics student, generally when you sum together a lot of random variables following a specific distribution you end up with basically the same distribution (scaled by the N random vars). So a lot of sigmo
427.
by ImaCake 5y ago
Like you say, we couldn’t even do GoF when HIV and pandemic influenza became a thing. Why take seriously the feeble efforts of humans to recreate evolution in a lab when the real thing has demonstrated it’s terrifying effectiveness many man
428.
by ImaCake 5y ago
Not wow. This is routine. The NIH has a policy to let researchers delete data from the sequence archive for various reasons. The reason they deleted it is very suspect, but the actual act is unremarkable and doesn’t implicate the NIH.
429.
by ImaCake 5y ago
I sought it out after seeing this link and found it to be very unimpressive. Science would do well to delete this article spruiking pretty trash science. P-values seem to be carefully hidden (not in the tables) and as far I could tell were
430.
by ImaCake 5y ago
Whatever your opinion on metformin this study is not really providing strong enough evidence to take seriously. No one should give it any attention, except the researchers who will try and do a better one next time and hopefully can prove&#
431.
by ImaCake 5y ago
This is a good way to put it. Twitter has a nasty habit of pushing politics on your feed no matter how many times you tell it not to. Digital nukes to clean up silicon valley's BS seems appropiate to wrest back some control. I can thin
432.
by ImaCake 5y ago
Yes, regression models do shows that IQ correlates with socioeconomic status. But remember that our statistical techniques often tell us about what factors matter on average . In something as messy as human IQ there are going to be people
433.
by ImaCake 5y ago
I read that sentence as they think SAT scores are correlated with but not causal for MIT student success. You would need to do a randomised controlled trial or a mendelian randomisation analysis (requires a lot of genotyping of students)
434.
by ImaCake 5y ago
What does this even mean? Are you responding to the link?
435.
by ImaCake 5y ago
Quite a bit. Table 1 is standard fare in human clinical trials and you could certainly check the summary stats in it for sanity. But you would find a lot of edge cases where your automated system would struggle. This is sorta done for meta-
436.
by ImaCake 5y ago
Randomised trials are for removing bias. You can certainly run precision medicine genomics randomised clinical trials. They are rarely done because so far our ‘omics tools haven’t been good enough to use, but that is changing now.
437.
by ImaCake 5y ago
I am guided by the irrefutable mathematics which has more certainty than any of the actual prose that explains it.
438.
by ImaCake 5y ago
No there is no reason to be skeptical of the author here because he based his evidence on statistics. As the author describes, the p-values listed are effectively impossible to get from real data. Because of the magic of mathematics, we kno
439.
by ImaCake 5y ago
My close family circle is against the vaccine mandates now, as am I. Although we all supported them initially. So it is hard for me to gauge the general opinion on the mandates. I suspect support is waning fast with high vax rates and the r
440.
by ImaCake 5y ago
I think the timing is right for this. Or at least it is getting close to the right time. Case Fatality Rate in heavily vaxxed populations is getting below seasonal influenza so the burden on society just isn’t as high as it was. The threat
441.
by ImaCake 5y ago
Non-substantive comments aren’t really welcome here. If you disagree with someone, explain why. HN respects a well worded argument.
442.
by ImaCake 5y ago
Don’t these kind of things happen whenever a war or pandemic happens? Showing your papers was important during WWI and WWII and I am aware of plenty of quarantines and mask mandates associated with previous cholera/TB/flu pandemic
443.
by ImaCake 5y ago
South Australia and the Northern Territory in Australia are on UTC+10:30 as well. We also do daylight savings per state. So, although NSW and QLD are both on the same UTC+11:00 timezone for the summer months NSW is 1 hour ahead because it h
444.
by ImaCake 5y ago
Another way to speed grep up is to use something like ripgrep. Something I picked up lately, as a noob with bash scripting, is that you can run a whole bunch of things from a single bash script and they will be automatically allocated to di
445.
by ImaCake 5y ago
Totally agree with this. My work and study involves a fair amount of statistics. Yesterday I got accidentally nerd sniped by some bad date based numerology which I promptly spent 20 minutes angrily demolishing. It would have been nice to no
446.
by ImaCake 5y ago
If you are on iOS you can, and should, use the App Limits functionality within Screen Time in settings. It won’t solve your problems, but it will help nudge you away from doom scrolling.
447.
by ImaCake 5y ago
An Australian bank I used has used their 2FA phone number to send me marketing messages about loans. I was absolutely furious about it. 2FA numbers should not be used for your marketing team’s sleazy trash.
448.
by ImaCake 5y ago
I didn’t enjoy 1984. If you have been exposed to those ideas elsewhere the book just doesn’t work. I did however love his memoir of his time fighting as a socialist volunteer in the Spanish civil war [1]. Very insightful read and clearly sh
449.
by ImaCake 5y ago
Yes, possible DNA sequences do not occur with equal frequencies. The whole point of selection pressure is that it selects for specific sequences. The same sequence occurring in a host species and a parasite is also not surprising. Rare even
450.
by ImaCake 5y ago
Yes and they are frustrating to see as someone with some understanding of molecular biology. The science is so far very clear cut that there is no evidence for a lab engineered virus and only circumstantial evidence for a lab leak (but plau

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