Gatsky

111 ms·

1. 1201.▲
   by Gatsky 8y ago

   This is an almost perfect article, and I don’t really care about surfing at all. Brilliant writing.
2. 1202.▲
   by Gatsky 8y ago

   I work in Oncology. A mobile battery service came over to replace a flat car battery. I was chatting to the guy while he was changing it over, and he said quite casually "Is it true what they say, that cancer has been cured and the pha
3. 1203.▲
   by Gatsky 8y ago

   I don't know how you can legitimately think this question is even worth asking? What do you think hospital staff do all day, deliberately try to ignore the obvious and torture the patient as much as possible?
4. 1204.▲
   by Gatsky 8y ago

   Totally, totally agree. The threads on healthcare are the second lowest quality content on HN (after cryptocurrency). Maybe this is because HN readers are pissed off by the healthcare system. Guess what, so are the people that work there. E
5. 1205.▲
   by Gatsky 8y ago

   This argument falls down because social media companies expend a lot of effort getting you to use their platform as much as possible. Why keep a snake that’s trying to bite you in your pocket?
6. 1206.▲
   by Gatsky 8y ago

   Terminals don’t suit this approach of trying to get an overview of what a program does. Personally I find trying to get an overview of a complex program/concept/project/anything quite taxing and laborious. Terminals are a wel
7. 1207.▲
   by Gatsky 8y ago

   My theory is this - obviously they are closely matched. Losing in the 12th game would make Caruana very hungry to come back again and again. Now, consider what happens if Carlsen crushes Caruana in the rapid or blitz rounds - this sends the
8. 1208.▲
   by Gatsky 8y ago

   The attempted CPR scene is still one of the most surprising things I’ve seen in a movie.
9. 1209.▲
   by Gatsky 8y ago

   No this is not correct, look up modern whole genome pipelines. Standard read lengths are 75-150 base pairs. Whole genome alignment has never been done with BLAST or BLAT (this would take an extremely long time). BWA is most commonly used. R
10. 1210.▲
    by Gatsky 8y ago

    I wouldn’t rule out 2. It works quite well, the dual alignment method is used in the research setting for human tumours grown in mice for example. Of course, a very motivated adversary would work this out, but you could use more unusual org
11. 1211.▲
    by Gatsky 8y ago

    Interesting. To be honest, if someone is able to collect intact tissue from you without your knowledge, there is no way to hide. If you can control the donation then it is different.
12. 1212.▲
    by Gatsky 8y ago

    Interesting to think about how you can ensure your anonymity and still take advantage of a cheap genome!! Some preliminary ideas: - misidentify yourself (eg get a few friends and submit each other's samples) - mix your DNA with a mamma
13. 1213.▲
    by Gatsky 8y ago

    Here here, you are both doing a tough job really well.
14. 1214.▲
    by Gatsky 8y ago

    Recommend you read this for some perspective on the issue. Indra Nooyi’s story opened my eyes a lot: https://www.cnbc.com/2018/10/03/indra-nooyi-shares-a-work-re...
15. 1215.▲
    by Gatsky 8y ago

    This isn't amazing. It is just a matter of priorities. There are many other things that need to be addressed first to ensure the patient gets onto the therapy they need. In my experience counselling people about interventions far more
16. 1216.▲
    by Gatsky 8y ago

    If you can find a way, try at least once to taste freshly pressed olive oil (by fresh I mean you are standing next to the oil press). This way you know for sure it hasn’t been blended or tampered with. My grandparents would pick olives and
17. 1217.▲
    by Gatsky 8y ago

    NuSI also funded a study by Kevin Hall which showed no effect on weight loss of isocaloric diets with different macronutrient composition, to be fair.
18. 1218.▲
    by Gatsky 8y ago

    This is wage economics 101, people have a visceral reaction to any evidence of unfairness. The same issue occurs in a slowing economy, where in an efficient market you would want to reduce costs by reducing wages, but in practice this is im
19. 1219.▲
    by Gatsky 8y ago

    Landing in the US for a very short trip I didn’t want to draw cash out (and have to store the notes for the next trip or change them back to local currency), and so I couldn’t tip people that needed to be tipped. Then I tried drawing cash f
20. 1220.▲
    by Gatsky 8y ago

    Fascinating and an excellent point, thanks.
21. 1221.▲
    by Gatsky 8y ago

    This is definitely true. This surgeon looks a bit foolish, he is seemingly unaware that there is a long history of medical educators complaining that the current generation are worse at X because of Y. Often it biased by a couple of outlier
22. 1222.▲
    by Gatsky 8y ago

    Paper isn’t even that bad really, just stating the obvious. Academia isn’t built to cope with well funded adversaries. Journalists handle the heat much better, at least the NYT got hold of it.
23. 1223.▲
    by Gatsky 8y ago

    Important to add that plants are the only carbon removal technology with a successful track record. As global warming devastates more of the biosphere, there will be perhaps less opposition to GMO plants engineered for maximum sequestration
24. 1224.▲
    by Gatsky 8y ago

    > We need to figure out what form of excercise gives the most benefit for unit of time spent. Retrospective observational studies like the one in the original post aren't going to to that though. Although I agree with you in princip
25. 1225.▲
    by Gatsky 8y ago

    Yes! I agree the HIIT research is great and very interesting and impactful - they designed and implemented an intervention with a control group and measured other correlative variables including muscle biopsies. And as you say the results a
26. 1226.▲
    by Gatsky 8y ago

    This is the best comment I have seen on HN all year.
27. 1227.▲
    by Gatsky 8y ago

    If there is one universal truth of human biology, it is that exercise is good. It is good if you do a bit or a lot, if you are young, old, male, female, trans, pregnant, trying to get pregnant, single, married, divorced, depressed, a smoker
28. 1228.▲
    by Gatsky 8y ago

    Your comment is ridiculously over the top. Not sure why you are getting so emotional about a nicely packaged bunch of observational studies.
29. 1229.▲
    by Gatsky 8y ago

    They are all observational studies, usually with small cohorts. Same problem with nutrtitional science and psychology. History tells us again and again these results are biased, unduly influenced by the investigators and often overturned (e
30. 1230.▲
    by Gatsky 8y ago

    Remember that the author is financially incentivised to make claims about large effect sizes of sleep deprivation, and to infer causality where it may or may not exist.