Gatsky

70 ms·

751.
by Gatsky 6y ago
This isn't the right point to make. There are a lot of unnecessary animal experiments because the way in which experiments are planned is very unprincipled. in silico approaches have great potential to improve the efficiency of animal
752.
by Gatsky 6y ago
This seems a little low value. It needs to be shorter for one. I don't really get their point about Color genomics. This company offers DTC a product which genetics labs already do everywhere. There are a lot of available resources for
753.
by Gatsky 6y ago
HN is social media?
754.
by Gatsky 6y ago
There are plenty of self-absorbed and self-congratulatory people who do nothing. I'm inclined to give artists a free pass. Authenticity is so endangered these days. After all, you can just ignore them, which is in fact a terrible punis
755.
by Gatsky 6y ago
This could be a documentary about my research career.
756.
by Gatsky 6y ago
Backups are the default solution. But my understanding of this UCSF case is that their system was compromised and then ransomwared. In this situation, the attacker could interfere with your backup system for several weeks or even spoil exis
757.
by Gatsky 6y ago
Is there a way to restrict encryption at a hardware level? The conditions where you would like to voluntarily encrypt data are usually quite rarefied. Allowing any sort of encryption activity on your system seems like a hazard these days.
758.
by Gatsky 6y ago
Can’t believe the article doesn’t mention why it is called the Silurian Hypothesis [1]! [1] https://en.m.wikipedia.org/wiki/Silurian_(Doctor_Who)
759.
by Gatsky 6y ago
I have to assume things were backed up, and the attackers were deep enough in the system to find or delete the backups. Anyway, I wonder how this payment was made...
760.
by Gatsky 6y ago
Apparently he added the ‘Klay’ to his name because he wanted to add a ‘maker’ element to it. I mean, this a bad prognostic sign if there ever was one in an engineering company.
761.
by Gatsky 6y ago
Great comment, thanks. HN just keeps delivering. It is almost impossible to believe how much embedded technical knowledge is lurking here. You could colonise Mars with it.
762.
by Gatsky 6y ago
I agree, holding up GWAS as some kind of lesson about scientific progress seems pretty silly. I don't think the 'sober experts' deserve shame and humiliation considering that PGSes have had minimal impact on human health.
763.
by Gatsky 6y ago
> One advancement has come in the ability to manufacture refractory metals, which are extraordinarily resistant to heating. https://en.wikipedia.org/wiki/Refractory_metals The melting point of tungsten is astonishin
764.
by Gatsky 6y ago
I thought I was going crazy when I first noticed the chronostasis effect on my watch (that is where the ticking second hand seems to stick in place when you first glance at it). Years later by chance I came across a paper explaining the mec
765.
by Gatsky 6y ago
Speaking completely and only for myself, possibly because the people writing the blogs have grown and developed, whereas I haven't. How much extra insight does one need?
766.
by Gatsky 6y ago
This could be partly because America has quite low wages.
767.
by Gatsky 6y ago
You misunderstand. I am definitely not anti-science. The point is we would probably be much further ahead and have many more impactful discoveries if this sort of nonsense wasn't happening, and good people who want to improve the world
768.
by Gatsky 6y ago
Did anyone think this wasn't happening? Science operates as a priesthood more than anything. Universities orginally emerged out of schools for religious instruction, to train Catholic clergy, and I'm not sure how far we have come
769.
by Gatsky 6y ago
It causes vestibular symptoms. This creates the sensation of motion without movement. Incidentally, if you’ve never had true vertigo, it is very disconcerting how much a sensory organ malfunction can affect your perception of the world. It
770.
by Gatsky 6y ago
To be fair, CPAP was originally developed for people with severe sleep apnoea and other neuromuscular disorders that have no other option.
771.
by Gatsky 6y ago
Looks like atomic rez is only possible with certain very stable proteins. Hopefully the tech will improve to allow broader application.
772.
by Gatsky 6y ago
A top tier journal has 3 papers with >500 citations that turned out to be bullshit in the last 10 years. One of them is probably the premiere example of academic misconduct in the last 50 years, catalysing the anti-vax movement and causi
773.
by Gatsky 6y ago
Well there were people that thought books were the work of the devil when they first came out. It takes a 2 or 3 generations to get the most important ideas completely accepted. The Flynn effect is helpful here.
774.
by Gatsky 6y ago
You don't seem to be reading my comments. I agree with you that pre-print servers are not useless, and that prestigious journals are also not useless. Pre-print servers obviously have a lot of questionable content, this is immediately
775.
by Gatsky 6y ago
I was asked to provide examples of the Lancet's poor track record, which I have done. I am not trying to prove it is better or worse than any other journal.
776.
by Gatsky 6y ago
Specifically I am praising pre-print servers in the current crisis, not in general. I don't propose they can replace journals wholesale in the near future. The harm done by bad research in the Lancet is colossal because the results are
777.
by Gatsky 6y ago
Of the top 10 most highly cited papers that have been retracted, 3 of them are in the Lancet, more than any other journal [1]. [1] https://retractionwatch.com/the-retraction-watch-leaderboard...
778.
by Gatsky 6y ago
I am a healthcare professional, and I've published in one of the Lancet Journals. I understand perfectly fine. Here's the thing - The Lancet is not impactful. Researchers choose to publish their impactful research in The Lancet. O
779.
by Gatsky 6y ago
I gave up reading The Lancet some time ago. They have a poor record frankly with this kind of thing, Andrew Wakefield et al chief among them. They should have been cancelled over that one. Anyway, the larger point is that these established
780.
by Gatsky 6y ago
It is definitely not trivially true about anything. A golf ball can be modelled easily. You are adding external complications to the system. An electron can be impossible to model if you inject it into a complex system. Anyway the point is

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