DrAwdeOccarim

11 ms·

91.
by DrAwdeOccarim 5y ago
Totally agree. I wonder what other companies can do similarly.
92.
by DrAwdeOccarim 5y ago
I like this idea. Thanks!
93.
by DrAwdeOccarim 5y ago
Yea, I assume it would be something like cutting the day in half. PG said to put the calls at the end of the day, so it didn't feel like an interruption. I can see how that would work; similar to what you're saying. I wonder if to
94.
by DrAwdeOccarim 5y ago
I have never heard of this maker vs manager schedule thing before. It really resonates with me. I just finished a rotation as a primary contributor on leave from my manager role and was having a real hard time telling people I had to cancel
95.
by DrAwdeOccarim 5y ago
Totally. With a masters, starting salary is $120k, so much more in line with OP. Also, OP is total comp, which a BS hits with equity and bonus targets.
96.
by DrAwdeOccarim 5y ago
Just to add an additional avenue for any people earlier in their career, starting salaries for research associates (bench-based wet lab work) in the Boston area right now, fresh out of undergrad with a 4-year degree, is $100k.
97.
by DrAwdeOccarim 5y ago
Maybe at your place of employment you won't get fired for not keeping your vaccinations up to spec, but there are many employees that have had vaccine mandates for decades...nearly every hospital, most research laboratories (especially
98.
by DrAwdeOccarim 5y ago
Yea, the fuzziness comes from protons shuttling about, tunneling around, electrons moving in cycles with phosphates. It's all just vibrating, bumping and bumbling about. I remember how blown my mind was when I first learned that all re
99.
by DrAwdeOccarim 5y ago
Reminds me of biological metabolic systems. All loops and branches…
100.
by DrAwdeOccarim 5y ago
Thank you for speaking my language. I couldn't parse through the other comments. To build on your thoughts, curiosity for me is the short-circuit ability to feel the fun chemicals just by thinking. That moment of aha connection is what
101.
by DrAwdeOccarim 5y ago
I did some reading just now on state vs trait curiosity and I'm having a hard time understanding the difference. Can you give me an example?
102.
by DrAwdeOccarim 5y ago
it boils down to costs. spinning up some code on your laptop is effectively free. of course your time, electricity, laptop depreciating, etc. cost money, but it's negligible if you're just taking a break from earning your living i
103.
by DrAwdeOccarim 5y ago
i appreciate the vote of confidence! to assuage your concerns, i'm part of the research planning team at a major biopharma. so funding, executing, and analyzing these kinds of experiments is my day job : )
104.
by DrAwdeOccarim 5y ago
industry. i'll just say it plainly. that's where you can fund more unestablished scientists. the vc world, the smart ones, are now funding moonshot ideas from younger scientists in ways academic science funding methods will never
105.
by DrAwdeOccarim 5y ago
Easier said than done, but yes most mRNA companies are trying the non-personalized and personalized cancer vaccine idea. The issue is the immune system is held back, like a big bouncer holding you back in a fight. Checkpoint inhibitors remo
106.
by DrAwdeOccarim 5y ago
Sadly, I agree 100%. Time and again I see labs/papers/companies trying to "target" cancer cells for specific killing. What we are all awaking up to now in the field is the only way to reliably achieve durable responses y
107.
by DrAwdeOccarim 5y ago
Really fascinating! I wonder if these cells all have defects in innate immune sensing of cytosolic DNA. Like, do cGAS/MAPK/etc. require linear for recognition like RIG-I does for dsRNA or are they all mutated/shutdown in thes
108.
by DrAwdeOccarim 5y ago
I wouldn't mind a toggle switch in settings that requests me to push "Yes" if I place my phone on a wireless charger. If you leave this function off, it just charges (for people who don't mind the risk).
109.
by DrAwdeOccarim 5y ago
Thank you for sharing that link. I always wondered why phage therapy isn't more widely developed. This feels like an example of an exponential tech improvement that our linear democratic institutions are having trouble adapting to. I w
110.
by DrAwdeOccarim 5y ago
This is a pretty exciting part of the mRNA field. There are some mutations that cause cancer (like G12D, G12V, G13D or G12C in KRAS) which allows you to make a single vaccine that can be used by anyone with those mutations. There is also a
111.
by DrAwdeOccarim 5y ago
It's such a shame, too. You can likely re-freeze the spikevax vials with partial shots to be used at a later date, but that's too uncontrolled to add to the EUA/BLA label. Comirnaty is (was) in phosphate buffer and saline, wh
112.
by DrAwdeOccarim 5y ago
Growing up surrounded by reasonable adults is a privilege, I've learned.
113.
by DrAwdeOccarim 5y ago
Yes! Wow, I haven't thought about this concept in _decades_
114.
by DrAwdeOccarim 5y ago
Yep, these apps definitely sparked my interest in linux as well.
115.
by DrAwdeOccarim 5y ago
Def. kept a list of us/pws for the local dial-up. Totally was at a good friend's house years later and discovered his dial-up username was one of my list I used often. rofl, that killed me at the time. I never told him!
116.
by DrAwdeOccarim 5y ago
I lived a very similar story. I fondly remember dialing up to the local BBS on my 2nd grade library computer (92,93) with ATT or ATDT [phone number]. And throughout elementary and middle school getting in tight with the sysadmins, eventuall
117.
by DrAwdeOccarim 5y ago
Completely agree. Its like a very specific point in time where not a ton of people experienced the same wonder.
118.
by DrAwdeOccarim 5y ago
Yea, same 98,99 window for me doing the same shit. This thread is crazy.
119.
by DrAwdeOccarim 5y ago
Woah, totally! I feel the need to write this one down. I was in high school when BO arrived. We had such a blast scanning the local dial-up ISP since we know the subnet block they always used, it was fast because it was all within their har
120.
by DrAwdeOccarim 5y ago
I have always wanted to build one, but since I keep my only cat indoors I never really had a reason to invest the time.

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