CreRecombinase

7 ms·

31.
by CreRecombinase 6y ago
Even Bell Labs wasn't suddenly Bell Labs though. Even when Bell Labs was "Bell Labs", was it ever profitable for those who were footing the bill (as opposed to society at large, which it obviously was)?
32.
by CreRecombinase 6y ago
You wanted type-safety and to replace macros, but then you went back to C?
33.
by CreRecombinase 7y ago
I don't know about illogical, but I think your intuition that zoonotic transfer is unlikely because it hasn't happened in the recent past is not a good one.
34.
by CreRecombinase 7y ago
If you can get down with emacs, then org mode had you covered: https://orgmode.org/manual/Paragraphs.html
35.
by CreRecombinase 7y ago
How much of the BioJulia stuff would you say currently works? It looks like a lot of repos have been created, and the scope is pretty impressive (looks like there are repos for everything from structural bioinformatics to population geneti
36.
by CreRecombinase 7y ago
R has some really excellent builtin numerical and statistical routines that are exposed via a C API: https://colinfay.me/r-installation-administration/the-standa...
37.
by CreRecombinase 7y ago
Anything in your headers is (more or less equivalent to being) copy-pasted into your own code. Many dependencies are header-only (which is the only option I'm aware of if the code is templated).
38.
by CreRecombinase 7y ago
What didn't you like about the packaging system? Even if you hate R the language, R has among the most user-friendly, cross-plaform packaging systems I'm aware of.
39.
by CreRecombinase 7y ago
I once read somewhere that the time to compile Linux from source on high-end desktop hardware has remained remarkably stable over the years.
40.
by CreRecombinase 7y ago
Even if your job is beyond statistics and data processing, you're probably using R because the core of what your team is doing is statistics and or data processing. If that's the case, and if you're the computationally sophis
41.
by CreRecombinase 7y ago
It's so crazy easy to start R in gdb: R -d gdb that's it!
42.
by CreRecombinase 7y ago
What is "actually programming"? Is fighting with your package manager (I'm looking at you python) "actually programming"? Is re-implementing functionality that exists elsewhere in the hipster language du jour (e.g
43.
by CreRecombinase 7y ago
This is a really great question. The fun thing about population genetics, (as opposed to the more experimental fields in biology) is that we can actually enumerate the forces (mutation, selection and random drift) that are acting on our su
44.
by CreRecombinase 7y ago
This is exactly what HDF5 was built for. Figuring out how often to persist to disk is going to depend on a number of factors. If you want to get fancy you can dedicate a thread to I/O but that gets hairy quickly. You also might want to
45.
by CreRecombinase 7y ago
C++11 vs C++14/C++17/C++20 is not python2 vs python3. Because of the emphasis on backwards compatibility, you can often just recompile your C++11 project with the new version of the standard and everything should just work. Back
46.
by CreRecombinase 7y ago
I think the answer to the question "should I apply X refactoring technique to this function Y?" obviously has to depend on both X and Y. There's clearly a trade-off here. If I have a free function foo(x) that I want to wo
47.
by CreRecombinase 7y ago
Because if you need to branch based on type more than a few times in your function it can get pretty hard to read. Am I right that the basis of your complaint is that it's now harder to find all the members of (what you'd call in
48.
by CreRecombinase 7y ago
If you want to treat R like awk, you should really check out the littler package, a super useful R package which provides an alternative to both Rscript and R CMD BATCH designed for writing one-liners https://github.com/edde
49.
by CreRecombinase 7y ago
If you don't think you need a better solution then you have to admit you need a better argument; it seems like a lot of voters disagree with you.
50.
by CreRecombinase 7y ago
> we can conclude that the coin is weighted in some way with P=0.03125 No we can't. There are 2 (related) reasons for this. The first is that to say "after experiment X, we can conclude thing Y is happening with probability .
51.
by CreRecombinase 7y ago
I'd argue that p(H0|x) is also (in most cases) pretty uninteresting from a scientific perspective, and so the whole "publish all the p-values" solution I think is only fighting half the battle. Gelman does a much better job
52.
by CreRecombinase 7y ago
This is a a really common misconception about p values (that they can be interpreted as p(H0|x), or "probability of the null hypothesis given the data") when a p-value is in fact p(x|H0), or "probability of observing data at
53.
by CreRecombinase 7y ago
This article is total trash. All the articles cited in this article are trash.
54.
by CreRecombinase 7y ago
Your moral obligation is to do what's in your contract to the best of your ability, and not to put anything in the contract that you can't be certain you can deliver on.
55.
by CreRecombinase 7y ago
I think the argument "because I wasn't deceived by the deceptive behavior, it isn't dishonest", isn't a great one. Even if you take a really legalistic view, and entirely ignore the ethical implications of this kin
56.
by CreRecombinase 7y ago
I could see the logic of the argument "these aren't dark patterns", or (to a lesser extent) "these are dark patterns(and therefore dishonest), but dishonesty isn't bad". I'm having trouble working through
57.
by CreRecombinase 9y ago
Do you have a source for that?
58.
by CreRecombinase 9y ago
"X power generation method isn't safe" just isn't a legit form of argument unless you can meaningfully compare it to 1)other power generation methods or 2)not generating that power. Climate change really is a catastroph
59.
by CreRecombinase 10y ago
It's quite rare to find GPUs being used in genetics.
60.
by CreRecombinase 10y ago
That's not how that works. CO2 is not a limiting reagent in photosynthesis.

More ›