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6177c40f
searching PlanetScale…
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12 ms
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121.
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6177c40f
4y ago
> “It should be noted that ecDNA is a feature of cancer and not healthy tissue, so that raises hopes that when we find ways to remove it – through drugs or some form of therapy – then it will not have unpleasant side-effects" Hopefu
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A Guide to DIYbio (2021)
(thatmre.medium.com)
1 points
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6177c40f
4y ago
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0 comments
123.
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6177c40f
4y ago
Unfortunately, doctors might be replaced by diagnostic AIs. It'll be AIs all the way down by then.
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The Last of Us: Perspectives from an epidemiologist and a plant scientist
(yourlocalepidemiologist.substack.com)
2 points
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6177c40f
4y ago
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0 comments
125.
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Killer Yeast and Smart Fungicides (2016)
(inverse.com)
1 points
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6177c40f
4y ago
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0 comments
126.
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6177c40f
4y ago
My understanding is that we don't even know for sure if it went extinct. We just don't know what it actually was/is. There's been a number of extant species that people have proposed as being silphium, but it's very
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New programmable gene editing proteins found outside of CRISPR systems (2021)
(broadinstitute.org)
9 points
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6177c40f
4y ago
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0 comments
128.
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6177c40f
4y ago
Derek Lowe is one of my favorite bloggers for sure. I also really like his "Things I Won't Work With" series, for example: https://www.science.org/content/blog-post/things-i-won-t-wor...
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6177c40f
4y ago
I've not read it myself, but An Elegant Defense [1] by Matt Richtel has come highly recommended to me. My understanding is that it takes a more human-interest angle, but also does a good job explaining how the immune system works and
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Wonderful Progress Against Severe Lupus
(science.org)
189 points
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6177c40f
4y ago
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31 comments
131.
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Understanding concentrated lactic acid sourdough (CLAS)
(brotgost.blogspot.com)
2 points
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6177c40f
4y ago
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0 comments
132.
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6177c40f
4y ago
I don't really understand how stack ranking is supposed to work. If 5% of employees must be ranked low, and they improve, they'll either be ranked low again or someone who wasn't ranked low will be ranked low- even if that pe
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6177c40f
4y ago
Because I doubt that the ranking system will be objective or even closely tied to any real measure of skill, performance, merit.
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6177c40f
4y ago
I hope some of those trees are still around somewhere waiting for someone to find them.
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6177c40f
4y ago
The contents of the mind should be sacrosanct- the deployment of technologies for reading the mind should go no further than it has except in medicine and research, and only then with explicit informed consent, of course. Honestly if this t
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6177c40f
4y ago
Has anyone ever done research to see if pervasive use of facial recognition has any real effect on reducing crime?
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6177c40f
4y ago
I read that initially as "Forthtran" and I can't tell if that sounds like a good idea or an awful one
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Powering the lunar base, version 2
(caseyhandmer.wordpress.com)
37 points
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6177c40f
4y ago
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38 comments
139.
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6177c40f
4y ago
> "manufactured by robots from local resources or asteroid mining." I feel like this just creates the new problems of operating, powering, and maintaining the robots, plus all the difficulties associated with mining asteroids a
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6177c40f
4y ago
This seems like a chicken-and-egg problem. Wouldn't you need power in the first place (and therefore transmission lines) to even extract and refine aluminium locally?
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Programmable editing a target base in genomic DNA without dsDNA cleavage (2016)
(ncbi.nlm.nih.gov)
2 points
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6177c40f
4y ago
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0 comments
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Wonderful Progress Against Severe Lupus
(science.org)
2 points
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6177c40f
4y ago
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0 comments
143.
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6177c40f
4y ago
If you want some more things that ChatGPT isn't good at, try to get it to form novel anagrams, palindromes, or other such wordplay. It's good at regurgitating textbook examples of those, but I found you can trip it up by asking it
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6177c40f
4y ago
Depends on the kind of math, it can do basic things reasonably consistently, but for other things it will confidently respond with the wrong answer (e.g. matrix arithmetic). In my testing, I found that it will absolutely fail every time at
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6177c40f
4y ago
This particular example doesn't really alarm me, but it does make me think about a scenario that I believe is plausible in the near future. Imagine a world where AI enables anyone to write complex programs, regardless of skill level. I
146.
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6177c40f
4y ago
There was a debate about whether it really couldn't be better explained by something other than life, then there was a debate as to whether they actually detected phosphine in the first place. See, for example, https://www.w
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6177c40f
4y ago
I feel like spectroscopy would only give you suggestive evidence of life at best, like if significant quantities of oxygen were detected in the atmosphere of an Earth-like exoplanet in the habitable zone. I think your best bet for direct de
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6177c40f
4y ago
Isn't WASP-39b a gas giant? Is it even possible for such a planet to have active volcanism?
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6177c40f
4y ago
Esoteric programming languages. When you remove the need for a programming language to be useful or understandable, what you get is a combination of challenging puzzles, humor, and some actually interesting ideas. Right now I'm actuall
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6177c40f
4y ago
How about you give it a try yourself and post the results to HN? I would be curious what you find.
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