The airframe is built to meet the intersection of hundreds of variables. Speed, stability, weight, repairability, and cost are a few. Needing to support a human

The airframe is built to meet the intersection of hundreds of variables. Speed, stability, weight, repairability, and cost are a few. Needing to support a human is just one of those factors. You can over-G an F-16 at 4G depending on airspeed and loadout. That's well below (trained) human tolerances. Sure, you can build a drone that can handle 1000 cycles of 16G turns, but it's likely not going to be cheap, repairable, fast, capable of carrying weaponry, etc.