Yes. Since the mechanism for memristors is either phase-change or filament production (by ion conduction), they eventually fail, basically just becoming a norma

Yes. Since the mechanism for memristors is either phase-change or filament production (by ion conduction), they eventually fail, basically just becoming a normal resistor. The number of cycles of some experimental devices is very high, though I don't know if anyone has done a true MTBF study on one.