While I don't have great advice to solve this, I'd like to point out a few things: 1. Don't project your desires on to her. You said she likes to talk on the p

While I don't have great advice to solve this, I'd like to point out a few things: 1. Don't project your desires on to her. You said she likes to talk on the phone, keeping in touch might be her favorite thing. Whereas something you value like some game/tech/hobby means very little to her. Talk openly with her about what she values in life and that's the best guide to what she can do for enjoyment. 2. People have to want to get out there themselves, they can and should have help, but ultimately it should be their desire. I'd say have a frank talk about her if getting out and meeting people is something she even wants (if she's not too sick to do so). Perhaps she's more interested in deepening her existing relationships. 3. Try various things, maybe it's hiking one week or for some months, maybe after that it's gardening or some classes. Maybe it's caring for a pet, there's just no way to know without trying some things. Finally it might be that a support group for her illness is best, perhaps it takes up most of her mental energy and sharing those concerns would lighten her up. 4. Talk to her. Open frank communication might take time, but I have a feeling it'll get the best results.