I do not think, that node.js is involved in the JavaScript apps for Windows. In your place I would test node.js the next time you do something like you did with

I do not think, that node.js is involved in the JavaScript apps for Windows. In your place I would test node.js the next time you do something like you did with Flask. If you now C#, I would not recommend to waste time to implement a node-based Windows GUI app.