It's always a trade-of between speed of development/maintenance vs performance. I think React is the best good enough compromise there is. It's really fast and

It's always a trade-of between speed of development/maintenance vs performance. I think React is the best good enough compromise there is. It's really fast and a joy to work with. But obviously, in certain very specific cases, vanilla javascript where you have 100% control over the javascript/DOM will be faster, there's no arguing about that.