>I guess my point is, can we do a full simulation of every screw, material, plumbing, liquid dynamics, weather dynamics, etc and augment those with known fail s

>I guess my point is, can we do a full simulation of every screw, material, plumbing, liquid dynamics, weather dynamics, etc and augment those with known fail scenarios and other fuzzy data to build out a real world KSP that predicts fails reliably? Frankly, no. You're wildly underestimating the complexity of the system.