Late but does that now work in all applications? 3years ago this worked in some applications, in others you had to use the old ctrl-a/ctrl-e (which couldn't be

Late but does that now work in all applications? 3years ago this worked in some applications, in others you had to use the old ctrl-a/ctrl-e (which couldn't be combined with shift) or cmd or control-left/right/up/down. Can't remember the details anymore, but I think I figured I needed at least three different combos for home/end back then.