The effects of supplements (primarily methylfolate and methylcobalamin) seems to depend on which mutation C677T, A1298, or both, and whether the person is homoz

The effects of supplements (primarily methylfolate and methylcobalamin) seems to depend on which mutation C677T, A1298, or both, and whether the person is homozygous or heterozygous. However, the biggest difference is having an answer, instead of doctors guessing and prescribing thyroxine or antidepressants (which can make life so much worse).