It could also be used to target genes for producing toxins (like the verotoxin produced by enterohemorrhagic Escherichia coli). Which would be less of an uphil

It could also be used to target genes for producing toxins (like the verotoxin produced by enterohemorrhagic Escherichia coli). Which would be less of an uphill battle against selection pressure for antibiotic resistance and still make the bacteria mostly harmless to humans.