1) pure science changes direction very, very slowly under the best of circumstances. 2) regulation strongly constrains funding by steering it towards drug disc

1) pure science changes direction very, very slowly under the best of circumstances. 2) regulation strongly constrains funding by steering it towards drug discovery. 3) people don't like being told they're doing it wrong, even when it is absolutely true. 4) the real goal of most researchers is to catalog metabolism, not to produce any way of treating aging.