The type of paintbrush you use does not need to limit the painting you can create, but it may mean you have to approach it's usage differently. Wireframes are

The type of paintbrush you use does not need to limit the painting you can create, but it may mean you have to approach it's usage differently. Wireframes are good; just give me a thick marker and some pencil (or a dry erase board) and i'm set. Sometimes you need to bring photoshop in, but rarely for concept work, more to produce parts. Also, where / when you stop designing is up to you. If you're not satisfied with the way things look, how you got there is not to blame, not enough iterations is. Start with a solid foundation and add nuances from there, instead of trying to build a full scale house out of paper.