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From all I know DNA replication has a very low error rate. I’m not a biologist, so I lack the expertise to accurately judge papers about this topic, but the one
by arrrg 11y ago
From all I know DNA replication has a very low error rate. I’m not a biologist, so I lack the expertise to accurately judge papers about this topic, but the one I found (through looking the topic up on Wikipedia) suggests a very low error rate:
“In total, these three discrimination steps result in an in vivo mutation rate estimated to be […] less than one error for every billion (or more) bases pairs copied […]” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639319/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639319/
- michaelhoffman 11y agoYour diploid genome is roughly six billion base pairs. That means six errors per duplication. But there will also be other errors introduced by DNA damage from other sources, and processes which have evolved to modify your genome (for example, V(D)J recombination).