there is an interesting analysis of the changes in their microbiota: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848073/ http://www.ncbi.nlm.nih.gov/pmc/articl

there is an interesting analysis of the changes in their microbiota: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848073/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848073/ "it can be concluded that the powerful stressful condition of prolonged containment in an isolated module had no “dramatic” effect on the state of the intestinal microbiota and did not lead to significant negative consequences for the health of the participants of the experiment. "