Both JamaicaVM and PERC seem to have favorable requirements when run with AOT compilation, and the JIT compilation didn't seem too onerous either. What problem

Both JamaicaVM and PERC seem to have favorable requirements when run with AOT compilation, and the JIT compilation didn't seem too onerous either. What problems have you run into? I ask because I'm in the process of spec'ing out a safety critical medical device, and JamaicaVM is the lead candidate at the moment.