Depending on the project, there is a good deal of statistics, as well as biology knowledge. As far as getting involved, I would check out current literature in

Depending on the project, there is a good deal of statistics, as well as biology knowledge. As far as getting involved, I would check out current literature in the general area of "Bioinformatics". Also consider searching for publications in Systems Biology, Computational Biology, Functional Genomics. Usually there are good articles coming out of Genome Biology, BMC Bioinformatics, BMC Genomics, as well as Nature, Cell, etc. I recently began a position as a Bioinformatics Software Engineer, after spending 8 years on Wall St building trading and financial analysis applications, which was somewhat of a switch (though my bachelor's is in Chemistry). Spending time reading the current literature has helped me get involved/engaged.