One disadvantage is that you miss all Power Nap features: https://support.apple.com/en-us/HT204032 https://support.apple.com/en-us/HT204032 In my opinion, you

One disadvantage is that you miss all Power Nap features: https://support.apple.com/en-us/HT204032 https://support.apple.com/en-us/HT204032 In my opinion, you don't miss all that much except for the following features: * Software updates download * Time Machine performs backups * Spotlight perform indexing