We use Doors for that. I think we tried TeamCenter for one project but it was a bag of hurt. The UI for doors is a little clunky (looks like a win95 app), but

We use Doors for that. I think we tried TeamCenter for one project but it was a bag of hurt. The UI for doors is a little clunky (looks like a win95 app), but it fulfills it's purpose. Doors equivalent functionality could be built with a web interface and a sql db backend. Maybe any kind of database would work, relational just makes the most sense to me. That said, assuming DO178B is similar to DO254, it's more about making sure you have a design process and that you are following it, and less about how good that process is.