I guess you mean clinical significance. http://www.bmj.com/content/348/bmj.g2130 http://www.bmj.com/content/348/bmj.g2130 This is a secondary issue. For most

I guess you mean clinical significance. http://www.bmj.com/content/348/bmj.g2130 http://www.bmj.com/content/348/bmj.g2130 This is a secondary issue. For most non-stats people, I wouldn't recommend the confidence interval as a measure of clinical significance. I'd rather look at the actual distribution of the two effects and view quantiles of the predictive interval. And, yes, in hypthoesis testing, p-values and confidence intervals are generally interchangeable. All they speak of is the overlap of the sample distribution of means, really.