3 ms·

>LSD is known to be safe in at least 1000x the normal dose I'd love to see a citation for that

by dEnigma 11y ago

Karunamon 11y ago
Erowid's got a MSDS for LSD that puts the LD50 at 50mg/kg, so for a 150 pound person, that works out to 3.4 grams. A normal dose of LSD is measured in micrograms, so the 1000x statement is at least very conservative.
tyho 11y ago
http://www.lycaeum.org/research/researchpdfs/1977_griggs_1.pdf http://www.lycaeum.org/research/researchpdfs/1977_griggs_1.p... https://www.erowid.org/chemicals/lsd/lsd_death.shtml https://www.erowid.org/chemicals/lsd/lsd_death.shtml Ok, well maybe not 'safe', but people have taken that amount and survived. It is certainly not something I would recommend.
- dEnigma 11y ago
  Thank you, I saw the erowid page before I posted and only read up to "more than 100 times a normal moderate dose of LSD" before I asked for a citation. Well, at least we know one shouldn't take 3200x the normal dose ;)
enkephalin 11y ago
if the ld50 is anywhere near that of mice or rats, even a 10000x dose could be non lethal.
DanBC 11y ago
They gave an elephant a very large dose, and it died, but they don't know if it was the LSD or the activity or the medical treatment that killed it. http://en.wikipedia.org/wiki/Tusko#The_elephant_on_LSD http://en.wikipedia.org/wiki/Tusko#The_elephant_on_LSD > "Tusko" was also the name of a male Indian elephant at the Oklahoma City Zoo. On August 3, 1962,[4] researchers from the University of Oklahoma injected (human use involves oral ingestion) 297 mg of LSD (lysergic acid diethylamide) to him, which is over 1,000 times the dose typical of human recreational use. Within five minutes he collapsed to the ground and one hour and forty minutes later he died. It is believed that the LSD was the cause of his death, although some speculate that the drugs the researchers used in an attempt to revive him may have contributed to his death.

>LSD is known to be safe in at least 1000x the normal dose I'd love to see a citation for that

by dEnigma 11y ago

>LSD is known to be safe in at least 1000x the normal dose I'd love to see a citation for that

Erowid's got a MSDS for LSD that puts the LD50 at 50mg/kg, so for a 150 pound person, that works out to 3.4 grams. A normal dose of LSD is measured in micrograms, so the 1000x statement is at least very conservative.

tyho 11y ago

http://www.lycaeum.org/research/researchpdfs/1977_griggs_1.pdf http://www.lycaeum.org/research/researchpdfs/1977_griggs_1.p... https://www.erowid.org/chemicals/lsd/lsd_death.shtml https://www.erowid.org/chemicals/lsd/lsd_death.shtml Ok, well maybe not 'safe', but people have taken that amount and survived. It is certainly not something I would recommend.

dEnigma 11y ago
Thank you, I saw the erowid page before I posted and only read up to "more than 100 times a normal moderate dose of LSD" before I asked for a citation. Well, at least we know one shouldn't take 3200x the normal dose ;)

enkephalin 11y ago

if the ld50 is anywhere near that of mice or rats, even a 10000x dose could be non lethal.

DanBC 11y ago

They gave an elephant a very large dose, and it died, but they don't know if it was the LSD or the activity or the medical treatment that killed it. http://en.wikipedia.org/wiki/Tusko#The_elephant_on_LSD http://en.wikipedia.org/wiki/Tusko#The_elephant_on_LSD > "Tusko" was also the name of a male Indian elephant at the Oklahoma City Zoo. On August 3, 1962,[4] researchers from the University of Oklahoma injected (human use involves oral ingestion) 297 mg of LSD (lysergic acid diethylamide) to him, which is over 1,000 times the dose typical of human recreational use. Within five minutes he collapsed to the ground and one hour and forty minutes later he died. It is believed that the LSD was the cause of his death, although some speculate that the drugs the researchers used in an attempt to revive him may have contributed to his death.