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Every small change in a molecule's structure can drastically change biological activity. And there is no way to predict what biological effects any change has i
by fabian2k 12y ago
Every small change in a molecule's structure can drastically change biological activity. And there is no way to predict what biological effects any change has in terms of side effects. You pretty much have to treat such a modified drug as an entirely new molecule.
- Nursie 12y agoYup. The problem with synthetic cannabinoids in particular is that (because of their relative popularity compared to other "Research Chemicals" or "Legal Highs") they get banned quickly so the makers have to find a new way to skirt around the law. This has resulted in lots of molecules being picked up from research literature that have never been tried in a living creature, let alone studied in humans. And some of the newest ones are totally off-piste, tweaks and modifications made to these already untested molecules such that cannabinoids are produced which can't even be found in the literature. There's also the drive to make stronger and stronger synthetic 'weed' and that causes problems too. It's not really possible to properly OD on the real thing. It's easy with synthetics.